ID A8ANV1_CITK8 Unreviewed; 197 AA.
AC A8ANV1;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=Probable UbiX-like flavin prenyltransferase {ECO:0000256|HAMAP-Rule:MF_01986};
DE EC=2.5.1.129 {ECO:0000256|HAMAP-Rule:MF_01986};
DE AltName: Full=Phenolic acid decarboxylase subunit B {ECO:0000256|HAMAP-Rule:MF_01986};
DE Short=PAD {ECO:0000256|HAMAP-Rule:MF_01986};
GN OrderedLocusNames=CKO_04098 {ECO:0000313|EMBL:ABV15164.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV15164.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV15164.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the non-oxidative decarboxylation and
CC detoxification of phenolic derivatives. Flavin prenyltransferase that
CC catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for
CC phenolic acid decarboxylase. {ECO:0000256|HAMAP-Rule:MF_01986}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2;
CC Xref=Rhea:RHEA:37743, ChEBI:CHEBI:43474, ChEBI:CHEBI:57618,
CC ChEBI:CHEBI:87467, ChEBI:CHEBI:88052; EC=2.5.1.129;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01986};
CC -!- SUBUNIT: Homododecamer. {ECO:0000256|HAMAP-Rule:MF_01986}.
CC -!- SIMILARITY: Belongs to the UbiX/PAD1 family. YclB subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01986}.
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DR EMBL; CP000822; ABV15164.1; -; Genomic_DNA.
DR RefSeq; WP_012134854.1; NC_009792.1.
DR AlphaFoldDB; A8ANV1; -.
DR STRING; 290338.CKO_04098; -.
DR GeneID; 45137737; -.
DR KEGG; cko:CKO_04098; -.
DR HOGENOM; CLU_074522_0_1_6; -.
DR OrthoDB; 9781577at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0106141; F:flavin prenyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1950; Flavin prenyltransferase-like; 1.
DR HAMAP; MF_01984; ubiX_pad; 1.
DR HAMAP; MF_01986; ubiX_pad_yclB; 1.
DR InterPro; IPR036551; Flavin_trans-like.
DR InterPro; IPR003382; Flavoprotein.
DR InterPro; IPR004507; UbiX-like.
DR InterPro; IPR032901; UbiX_pad_YclB.
DR NCBIfam; TIGR00421; ubiX_pad; 1.
DR NCBIfam; NF041206; VdcB; 1.
DR PANTHER; PTHR43374; FLAVIN PRENYLTRANSFERASE; 1.
DR PANTHER; PTHR43374:SF1; FLAVIN PRENYLTRANSFERASE PAD1, MITOCHONDRIAL; 1.
DR Pfam; PF02441; Flavoprotein; 1.
DR SUPFAM; SSF52507; Homo-oligomeric flavin-containing Cys decarboxylases, HFCD; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|HAMAP-Rule:MF_01986};
KW Detoxification {ECO:0000256|HAMAP-Rule:MF_01986};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW Rule:MF_01986};
KW FMN {ECO:0000256|ARBA:ARBA00022643, ECO:0000256|HAMAP-Rule:MF_01986};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602, ECO:0000256|HAMAP-
KW Rule:MF_01986}; Reference proteome {ECO:0000313|Proteomes:UP000008148};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_01986}.
FT DOMAIN 1..173
FT /note="Flavoprotein"
FT /evidence="ECO:0000259|Pfam:PF02441"
FT BINDING 9..11
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01986"
FT BINDING 36
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01986"
FT BINDING 87..90
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01986"
FT BINDING 122
FT /ligand="FMN"
FT /ligand_id="ChEBI:CHEBI:58210"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01986"
SQ SEQUENCE 197 AA; 21578 MW; 258D41043478F28F CRC64;
MRLIVGMTGA TGAPLGIALL QALRQMPTVE THLVMSKWAK TTIELETPYS ARDVAGLADY
CHNPADQAAT ISSGSFRTDG MIIMPCSMKT LAGIRAGYAE GLVGRAADVV LKEGRKLVLV
PREMPLSTIH LENMLALSRM GVAMVPPMPA FYNHPQTIDD ITQHIVARVL DQFGLEHPRA
RRWQGLQQAQ NFSQENE
//
