ID   A8AV99_STRGC            Unreviewed;       246 AA.
AC   A8AV99;
DT   23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=D-alanyl-D-alanine carboxypeptidase {ECO:0000313|EMBL:ABV10377.1};
DE            EC=3.4.16.4 {ECO:0000313|EMBL:ABV10377.1};
GN   OrderedLocusNames=SGO_0393 {ECO:0000313|EMBL:ABV10377.1};
OS   Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS   DL1 / V288).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=467705 {ECO:0000313|EMBL:ABV10377.1, ECO:0000313|Proteomes:UP000001131};
RN   [1] {ECO:0000313|EMBL:ABV10377.1, ECO:0000313|Proteomes:UP000001131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288
RC   {ECO:0000313|Proteomes:UP000001131};
RX   PubMed=17720781; DOI=10.1128/JB.01023-07;
RA   Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT   "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT   to competence signaling peptide.";
RL   J. Bacteriol. 189:7799-7807(2007).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000725; ABV10377.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8AV99; -.
DR   STRING; 467705.SGO_0393; -.
DR   KEGG; sgo:SGO_0393; -.
DR   eggNOG; COG1876; Bacteria.
DR   HOGENOM; CLU_054193_3_1_9; -.
DR   Proteomes; UP000001131; Chromosome.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd14852; LD-carboxypeptidase; 1.
DR   Gene3D; 3.30.1380.10; -; 1.
DR   InterPro; IPR009045; Hedgehog_sig/DD-Pept_Zn-bd_sf.
DR   InterPro; IPR003709; Pept_M15B.
DR   PANTHER; PTHR34385; D-ALANYL-D-ALANINE CARBOXYPEPTIDASE; 1.
DR   PANTHER; PTHR34385:SF1; PEPTIDOGLYCAN L-ALANYL-D-GLUTAMATE ENDOPEPTIDASE CWLK; 1.
DR   Pfam; PF02557; VanY; 1.
DR   SUPFAM; SSF55166; Hedgehog/DD-peptidase; 1.
PE   4: Predicted;
KW   Carboxypeptidase {ECO:0000313|EMBL:ABV10377.1};
KW   Hydrolase {ECO:0000313|EMBL:ABV10377.1};
KW   Protease {ECO:0000313|EMBL:ABV10377.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001131}.
FT   DOMAIN          91..220
FT                   /note="Peptidase M15B"
FT                   /evidence="ECO:0000259|Pfam:PF02557"
FT   REGION          38..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   246 AA;  27088 MW;  E4C2F2B0EC94058C CRC64;
     MTILLLLILT LVIGGTVIYF RPSLLKNLLS HVHVSSQVSS STKPSSSKSS ELTSSDSDLP
     KVSSADWNLV LVNRDNLQEE KMPSLTQVGE IRVDSRIAEN TRQFLAAAQA VAPGEILISG
     YRSRAEQEEL FNENVAAEEA KGLSHEEAVS AVQKQIQIPG ASEHQTGLAI DMSVPEGLED
     ELAAKIAQLA PQYGFVLRYP EGKSNITGVD FEHWHYRYVG VENAQYMQKH NLVLEEYIAL
     LKAAEK
//