ID A8B009_STRGC Unreviewed; 453 AA.
AC A8B009;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Histidine protein kinase ComD {ECO:0000313|EMBL:ABV09742.1};
DE EC=2.7.3.- {ECO:0000313|EMBL:ABV09742.1};
GN Name=comD {ECO:0000313|EMBL:ABV09742.1};
GN OrderedLocusNames=SGO_2146 {ECO:0000313|EMBL:ABV09742.1};
OS Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS DL1 / V288).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=467705 {ECO:0000313|EMBL:ABV09742.1, ECO:0000313|Proteomes:UP000001131};
RN [1] {ECO:0000313|EMBL:ABV09742.1, ECO:0000313|Proteomes:UP000001131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288
RC {ECO:0000313|Proteomes:UP000001131};
RX PubMed=17720781; DOI=10.1128/JB.01023-07;
RA Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT to competence signaling peptide.";
RL J. Bacteriol. 189:7799-7807(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000725; ABV09742.1; -; Genomic_DNA.
DR RefSeq; WP_012131078.1; NC_009785.1.
DR AlphaFoldDB; A8B009; -.
DR STRING; 467705.SGO_2146; -.
DR KEGG; sgo:SGO_2146; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_046138_2_0_9; -.
DR Proteomes; UP000001131; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ABV09742.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001131};
KW Transferase {ECO:0000313|EMBL:ABV09742.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 345..445
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
FT COILED 217..253
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 453 AA; 53637 MW; 781D5360489B0139 CRC64;
MIFTIILSLF PVIIQVFSYD FFYNKINRKK KINIKLIILF WGLIMVISFL YSLFLLLPDY
WKIFRDIFHY LFLLIQPLIF YKYFLIKRKE YENYLNLFLS FVIYLSVETS ETFLSVIISS
ITGDSFVKQH YDIFYIIINL LSLFIILKVV DFFDFYFEYY KEPIYKNDLY NVNKSYIVIH
ILLNISHWFS ENAHLNSFAS MIATIGFIMF LSTLFYLKSA REQYEKAKEI QQKKEEQRQL
QLYTDEIVGL YNEIRGFRHD YAGMLTSLQT GINSGDMKEV ERIFHNVLSQ ANISLRSDDY
TFFELNNVQD TALRSVLIQT IFKARECGVE IVFEMKDVIE TLPMKLLDLV RVASVLLNNA
VEGAAESPSK TMNVSLVKLD KEIVFVIQNS RQSRYINLEE IYEVGFSTKG ENRGLGLNNV
KEIIDKYDEV ILETDIETNY FIQVVRFKRK EKI
//
