ID A8B226_GIAIC Unreviewed; 723 AA.
AC A8B226;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Ankyrin repeat protein 1 {ECO:0000313|EMBL:KAE8302907.1};
DE SubName: Full=Protein 21.1 {ECO:0000313|EMBL:EDO82211.1};
GN ORFNames=GL50803_0088071 {ECO:0000313|EMBL:KAE8302907.1},
GN GL50803_88071 {ECO:0000313|EMBL:EDO82211.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO82211.1};
RN [1] {ECO:0000313|EMBL:EDO82211.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO82211.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8302907.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8302907.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO82211.1}.
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DR EMBL; AACB02000001; EDO82211.1; -; Genomic_DNA.
DR EMBL; AACB03000003; KAE8302907.1; -; Genomic_DNA.
DR RefSeq; XP_001709885.1; XM_001709833.1.
DR AlphaFoldDB; A8B226; -.
DR STRING; 184922.A8B226; -.
DR EnsemblProtists; EDO82211; EDO82211; GL50803_88071.
DR GeneID; 5702809; -.
DR KEGG; gla:GL50803_0088071; -.
DR VEuPathDB; GiardiaDB:GL50803_88071; -.
DR HOGENOM; CLU_382847_0_0_1; -.
DR InParanoid; A8B226; -.
DR OMA; DEVPHWR; -.
DR Proteomes; UP000001548; Chromosome 3.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF12796; Ank_2; 3.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548}.
FT REPEAT 572..604
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 723 AA; 78767 MW; 8B6E673857EC1FB3 CRC64;
MSILKTKAEW FAAVRAQDAD SILRSVHKHL GARNNLGDTA LITAVRARDV QIASLLLPFE
HSLLDSRGYP ALGIAIELDA PELVCLLAPL EENTPVPGYG SPLALAAACG AFRSLRILST
FLCDSSTGEH ETALNQAVRA RHYSMIETLL ETQAYAQKDL LDALDLCVDG SRSSVAIQQM
LQLALKFISS GSTLTLRAAL QTIQSITEEN TFLTESLIKM FAALRPIYSM VASNRDALLE
EKSTVSILLQ THTVMEQSEQ VQESIPQFMH SKKGAQKSIA DVVETLADNV ASTPLSSASI
ISKEVASNYL ETDDGKKLAT EVRNIYSLMA AQKDTLQVVQ SRFASLISAV AEFPGCSLPP
CTENGSLTPL MQAIIDNNMN AVLDTLLPYA GRRTDTGETA LMLAAQHGNV AAVKLLSTIE
YGMQDNQGKT ALRHALETNN YDSASVLIEV DQKRYTDTLR ESGWRCVDGT TCLFVALKNK
CSFSYKYLIS KEGNLSIGTL VTEEFGKIEV ASPLMLAVQK CRTDAIILLS PLAAGYVEPT
NKRSTLMLAA CSGNSTAVRI LAQYEAGLQD CQGYTALMYA AERNYVDIVE LLLPHESKLI
TNASSRWGSG HTALMIAAYN GCVETVAQLI PHEAGMVQAA PDIKQQYAGW SALVWAASSP
EASLACIEIL AEKESQHAQK ALDEVPHWRD DRLTIKQLLA PYLGYEQRAL SQRSQRRSRR
SVH
//
