ID A8BD82_GIAIC Unreviewed; 578 AA.
AC A8BD82;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 08-NOV-2023, entry version 47.
DE SubName: Full=CDP-diacylglycerol--serine O-phosphatidyltransferase {ECO:0000313|EMBL:KAE8304197.1};
GN ORFNames=GL50803_0017427 {ECO:0000313|EMBL:KAE8304197.1},
GN GL50803_17427 {ECO:0000313|EMBL:EDO80063.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO80063.1};
RN [1] {ECO:0000313|EMBL:EDO80063.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO80063.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8304197.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8304197.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO80063.1}.
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DR EMBL; AACB02000012; EDO80063.1; -; Genomic_DNA.
DR EMBL; AACB03000002; KAE8304197.1; -; Genomic_DNA.
DR RefSeq; XP_001707737.1; XM_001707685.1.
DR AlphaFoldDB; A8BD82; -.
DR EnsemblProtists; EDO80063; EDO80063; GL50803_17427.
DR GeneID; 5700644; -.
DR KEGG; gla:GL50803_0017427; -.
DR VEuPathDB; GiardiaDB:GL50803_17427; -.
DR HOGENOM; CLU_472113_0_0_1; -.
DR OMA; YANCVSI; -.
DR Proteomes; UP000001548; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 530..557
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 578 AA; 65013 MW; B48E0C677FFF14BC CRC64;
MEPKAAFALL ILFILVWVTA GYGLSHLMKS RTGSGANAMI RLCLGLGLIV SLLLYNGHTT
LALVLYIVCM AASTANILNL ETRTKSAKHT KWKPWLLGTQ ARLCITPYSE QCFYIPIFFF
LMIPRLQPVS SVIQAINPQS IDEQATYISL IDPALAMLFI ILSSWSNVTI RRQATRNTLR
SLFKHSCLYT CLFIQFLLND NKNLFHHDTN VFRILTFRRS LNVSHLEYFS NALLFIATLL
VTIEQFLSRV PQNWYANCVS ILNLLCGLLG IHFLVLPPGS TVSSGTLSVL VLSCIMMGQL
FDLFDGRVAE KWGSTKNGEL FDDVADATSF GIAVGLLIHH ISSSFVPYSS GLWSITLAGV
YIFCVFYRLV RFILNKRAQQ VKGGVYFFFG LPSPATATMA GLLCVLFEQD WTLSHFWFRT
LNLPLPMLKQ ITFSTSVLVL CLLTISSVPY PHLGRVLYRR GVLPQSFRIS VEALFVVSAI
YGMYYRTSIL ILYCLGSFSV LYLFTPVYAD KLGWYSRDFT IKEKHVETII LAQQKKIERL
ERMYTSALAK LKKLNAKVSS YNNSSASNSE ASSNVLPE
//
