ID A8BJG3_GIAIC Unreviewed; 122 AA.
AC A8BJG3;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Ribosomal protein L7Ae {ECO:0000313|EMBL:EDO78903.1};
GN ORFNames=GL50803_002825 {ECO:0000313|EMBL:KAE8303889.1}, GL50803_2825
GN {ECO:0000313|EMBL:EDO78903.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO78903.1};
RN [1] {ECO:0000313|EMBL:EDO78903.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO78903.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8303889.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8303889.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC machinery. {ECO:0000256|RuleBase:RU366039}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU366039}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000256|ARBA:ARBA00007337, ECO:0000256|RuleBase:RU366039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO78903.1}.
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DR EMBL; AACB02000021; EDO78903.1; -; Genomic_DNA.
DR EMBL; AACB03000002; KAE8303889.1; -; Genomic_DNA.
DR RefSeq; XP_001706577.1; XM_001706525.1.
DR AlphaFoldDB; A8BJG3; -.
DR SMR; A8BJG3; -.
DR STRING; 184922.A8BJG3; -.
DR EnsemblProtists; EDO78903; EDO78903; GL50803_2825.
DR GeneID; 5699463; -.
DR KEGG; gla:GL50803_002825; -.
DR VEuPathDB; GiardiaDB:GL50803_2825; -.
DR HOGENOM; CLU_084513_4_0_1; -.
DR InParanoid; A8BJG3; -.
DR OMA; HLTITIM; -.
DR Proteomes; UP000001548; Chromosome 4.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR InterPro; IPR018492; Ribosomal_eL8/Nhp2.
DR PANTHER; PTHR23105:SF38; NHP2-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00883; NUCLEARHMG.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366039};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU366039};
KW Ribosomal protein {ECO:0000313|EMBL:EDO78903.1};
KW RNA-binding {ECO:0000256|RuleBase:RU366039}.
FT DOMAIN 17..104
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
SQ SEQUENCE 122 AA; 13230 MW; 1933C0BAB656FB43 CRC64;
MPDARAVPLA SEAQSKRIYE LVDLAKNSRS ISRGMNEVTK ALNKGKARLV VLSADALPLE
LVLHLPEVCE DKGIAYIFVP SRQELGRSVG ISRQAVAVAI KAPRQGTALD DKLNIFLTEL
GH
//
