ID A8BLJ7_GIAIC Unreviewed; 654 AA.
AC A8BLJ7;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Ankyrin repeat protein 1 {ECO:0000313|EMBL:KAE8302773.1};
DE SubName: Full=Protein 21.1 {ECO:0000313|EMBL:EDO78634.1};
GN ORFNames=GL50803_0014834 {ECO:0000313|EMBL:KAE8302773.1},
GN GL50803_14834 {ECO:0000313|EMBL:EDO78634.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO78634.1};
RN [1] {ECO:0000313|EMBL:EDO78634.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO78634.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8302773.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8302773.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO78634.1}.
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DR EMBL; AACB02000024; EDO78634.1; -; Genomic_DNA.
DR EMBL; AACB03000003; KAE8302773.1; -; Genomic_DNA.
DR RefSeq; XP_001706308.1; XM_001706256.1.
DR AlphaFoldDB; A8BLJ7; -.
DR STRING; 184922.A8BLJ7; -.
DR EnsemblProtists; EDO78634; EDO78634; GL50803_14834.
DR GeneID; 5699196; -.
DR KEGG; gla:GL50803_0014834; -.
DR VEuPathDB; GiardiaDB:GL50803_14834; -.
DR HOGENOM; CLU_464204_0_0_1; -.
DR InParanoid; A8BLJ7; -.
DR OMA; EMGNEEC; -.
DR Proteomes; UP000001548; Chromosome 3.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF12796; Ank_2; 5.
DR SMART; SM00248; ANK; 13.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548}.
FT REPEAT 103..135
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 538..559
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 654 AA; 71679 MW; B6FBA8E15201EEB9 CRC64;
MGAGASSVSG APSVSPCAVT AAAVLQRLEG VSMGKVIEGC ERGWLAKALM GAHLLTPDCV
DIFERPPPIR GVYETTALIQ AVKENDETLF DQYLTQLSFR TNSGRTALMY AAELGRQQMA
ERLLDEAEVV DLSGKTALIY ALEAGHYDIA DMLIPYEVGK AGVTDLMFYA QTGNLDALLA
EQDDARAQDL SGHTALMVAV IHKNVKVAEL LLEEMALTTT KGVTALMLAA QRGYGELVYL
LATSTSTIEQ PTGKFSKRTG QQRMRPVKLR ELSNQTRDTG DSALMFAVKR GDILAACCLT
EELYLQDCTG KTALMHAAER GDAEMVKFLC SLMKKGDRVQ VDKKGRTALM YAAAQNYRAA
AEQLFLREQR FQDKSGRTAL SYALEHMAVD TISLLSPASV EGRFSKITQL MIDAACGKIS
EPLTPAQLVE VRQQDTSGRT ALMYAVLAGH TKAIEHLCIE VEDFAHGHES VLQMCIEAQK
LNCLQVLLLH VYEENVQINI PKLSLSIVDY ETDLLAAAEK NDSFGARTHI DQAGKLCNGW
TALMTAAYRG HIDIVKLLLC EVKLQNEKGW TALMLAVQTA QSEVVRLLAR YELGLKDNEG
ETALVKAIRW NAIDMIEVLL REKHVLTNNR QTALSVAMEM GNEECLKLLK APKL
//
