ID   A8F4W8_PSELT            Unreviewed;       205 AA.
AC   A8F4W8;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase {ECO:0000313|EMBL:ABV33202.1};
GN   OrderedLocusNames=Tlet_0636 {ECO:0000313|EMBL:ABV33202.1};
OS   Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 /
OS   TMO) (Thermotoga lettingae).
OC   Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC   Pseudothermotoga.
OX   NCBI_TaxID=416591 {ECO:0000313|EMBL:ABV33202.1, ECO:0000313|Proteomes:UP000002016};
RN   [1] {ECO:0000313|EMBL:ABV33202.1, ECO:0000313|Proteomes:UP000002016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC   {ECO:0000313|Proteomes:UP000002016};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K.,
RA   Richardson P.;
RT   "Complete sequence of Thermotoga lettingae TMO.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABV33202.1, ECO:0000313|Proteomes:UP000002016}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC   {ECO:0000313|Proteomes:UP000002016};
RX   PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA   Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA   DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA   Noll K.M.;
RT   "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT   the Thermotogales.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC   -!- SIMILARITY: Belongs to the KHG/KDPG aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006906}.
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DR   EMBL; CP000812; ABV33202.1; -; Genomic_DNA.
DR   RefSeq; WP_012002683.1; NZ_BSDV01000001.1.
DR   AlphaFoldDB; A8F4W8; -.
DR   STRING; 416591.Tlet_0636; -.
DR   KEGG; tle:Tlet_0636; -.
DR   eggNOG; COG0800; Bacteria.
DR   HOGENOM; CLU_077795_2_0_0; -.
DR   OrthoDB; 9802667at2; -.
DR   Proteomes; UP000002016; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   CDD; cd00452; KDPG_aldolase; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR000887; Aldlse_KDPG_KHG.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR031338; KDPG/KHG_AS_2.
DR   NCBIfam; TIGR01182; eda; 1.
DR   PANTHER; PTHR30246:SF1; 2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE; 1.
DR   PANTHER; PTHR30246; 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE; 1.
DR   Pfam; PF01081; Aldolase; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS00160; ALDOLASE_KDPG_KHG_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002016}.
SQ   SEQUENCE   205 AA;  21540 MW;  614E9046C2D3A155 CRC64;
     MDLVEKIVES GVVAVVRTDS PEKAVEICHA CKEGGIIAIE ITFSVPRAVE VIQQIDKELG
     NEILLGAGTV LDPYTAKIAI EAGAKYIVAP NLSEETALLC NKHRVPYIPG VLTPTEIVKA
     LELGVPLIKL FPASAVGPSY IKAIHGPLPQ AKLLPTGGVN VENVKDWIKA GAAAVGVGGG
     LTKGSRKEIA EKAKKLVQAV KEARE
//