ID A8F543_PSELT Unreviewed; 463 AA.
AC A8F543;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Dipeptidase, putative {ECO:0000313|EMBL:ABV33277.1};
GN OrderedLocusNames=Tlet_0711 {ECO:0000313|EMBL:ABV33277.1};
OS Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 /
OS TMO) (Thermotoga lettingae).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Pseudothermotoga.
OX NCBI_TaxID=416591 {ECO:0000313|EMBL:ABV33277.1, ECO:0000313|Proteomes:UP000002016};
RN [1] {ECO:0000313|EMBL:ABV33277.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K.,
RA Richardson P.;
RT "Complete sequence of Thermotoga lettingae TMO.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABV33277.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RX PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA Noll K.M.;
RT "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT the Thermotogales.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP000812; ABV33277.1; -; Genomic_DNA.
DR RefSeq; WP_012002758.1; NZ_BSDV01000001.1.
DR AlphaFoldDB; A8F543; -.
DR STRING; 416591.Tlet_0711; -.
DR KEGG; tle:Tlet_0711; -.
DR eggNOG; COG0624; Bacteria.
DR HOGENOM; CLU_031786_2_0_0; -.
DR OrthoDB; 9761532at2; -.
DR Proteomes; UP000002016; Chromosome.
DR GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.70.360; -; 2.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR010964; M20A_pepV-rel.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR NCBIfam; TIGR01887; dipeptidaselike; 1.
DR PANTHER; PTHR43808; ACETYLORNITHINE DEACETYLASE; 1.
DR PANTHER; PTHR43808:SF33; DIPEPTIDASE SAOUHSC_01868-RELATED; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00759; ARGE_DAPE_CPG2_2; 1.
PE 4: Predicted;
KW Dipeptidase {ECO:0000256|ARBA:ARBA00022997};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|ARBA:ARBA00022997};
KW Reference proteome {ECO:0000313|Proteomes:UP000002016};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 255..368
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 463 AA; 50905 MW; EFC444B0A7F49D17 CRC64;
MNKTVDEFVL VNSNKLFDAA SNLVKIKSVK SQPAGDGKPF GEGIAKALEA ALNMGKQWGF
NVKNIDGYAG HIEYGTKGKL FAVLGHLDVV PEGDGWTVDP YGGIIKDGYL WGRGSSDDKG
PTVAAIFALK AVKESRINPK NRIRIILGCD EESGWEGVKH YFEKEEIPIY AVTPDANFPI
IYAEKGIINY TITQHLHKNK DTQVVLLKGG EASNMVPQEA LAVLKPVREE ILEKLKEFTP
QNGAKVFWNI DGDELKIKIT GKSAHGSKPQ TGVNAISALL DFLRTIDINC EDLSTFLRTI
FAKIGYETDG TSLRIAGTDC IAGPLTVNLG TLRMDPEKIT AVINIRYPVF YSETMLTKQI
KEALKPLQVE PQNHLAPLFV SPDSELIKIL SEIYTDVTGQ KAELLTTGGG TYARAVPCGV
AFGPLLPGRL ETEHQPDERI ALDDLLLVAR IYAQLFYKIM TEW
//
