ID A8F6A0_PSELT Unreviewed; 412 AA.
AC A8F6A0;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Extracellular ligand-binding receptor {ECO:0000313|EMBL:ABV33684.1};
DE Flags: Precursor;
GN OrderedLocusNames=Tlet_1119 {ECO:0000313|EMBL:ABV33684.1};
OS Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 /
OS TMO) (Thermotoga lettingae).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Pseudothermotoga.
OX NCBI_TaxID=416591 {ECO:0000313|EMBL:ABV33684.1, ECO:0000313|Proteomes:UP000002016};
RN [1] {ECO:0000313|EMBL:ABV33684.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K.,
RA Richardson P.;
RT "Complete sequence of Thermotoga lettingae TMO.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABV33684.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RX PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA Noll K.M.;
RT "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT the Thermotogales.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC -!- SIMILARITY: Belongs to the leucine-binding protein family.
CC {ECO:0000256|ARBA:ARBA00010062}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000812; ABV33684.1; -; Genomic_DNA.
DR RefSeq; WP_012003165.1; NZ_BSDV01000001.1.
DR AlphaFoldDB; A8F6A0; -.
DR STRING; 416591.Tlet_1119; -.
DR KEGG; tle:Tlet_1119; -.
DR eggNOG; COG0683; Bacteria.
DR HOGENOM; CLU_027128_4_3_0; -.
DR OrthoDB; 9783240at2; -.
DR Proteomes; UP000002016; Chromosome.
DR CDD; cd06340; PBP1_ABC_ligand_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR028081; Leu-bd.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30483:SF37; ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN; 1.
DR PANTHER; PTHR30483; LEUCINE-SPECIFIC-BINDING PROTEIN; 1.
DR Pfam; PF13458; Peripla_BP_6; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 3: Inferred from homology;
KW Receptor {ECO:0000313|EMBL:ABV33684.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002016};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 22..383
FT /note="Leucine-binding protein"
FT /evidence="ECO:0000259|Pfam:PF13458"
SQ SEQUENCE 412 AA; 45565 MW; 4BD50CC4AF04822A CRC64;
MKKFFTLVVM FISILIFAED VIKIGAIFPL TGPAAATGVK IKYAIEVAQE IINGVYPDID
LDLAKSQGLS NLNGAKIQFI FADHQANPEL AMAEAERLIQ NEKVVALIGC YHSSATKPAS
QIAEKYGIPF VAGSSSSAAL TERGLKWFFR IAPHDGMETD FFFLYLNYLK EKYGANLSRV
AVVYIDNEYG VHASLMVKEK IKKYSGFNLV ADIKYPANVT NVDIEVQKIR AAKPDVIIHA
SYIGDMTMFV KKYKEFNVMP KVVLSFCGGY QDPQFVINLG KDANFFSGTN ATTSALFSKM
AILARINQLY KAKSGVDIDG PTLEDFASAM VIAEAINIAK STDPSKILEI LQTQTFSAPY
FVSGKIKFGP DGQNLYSASV MTQILDGIYE AVWPEAFQTK EPVPYFPEWN KR
//
