ID A8FDE0_BACP2 Unreviewed; 307 AA.
AC A8FDE0;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Kanamycin kinase {ECO:0000313|EMBL:ABV62257.1};
GN OrderedLocusNames=BPUM_1575 {ECO:0000313|EMBL:ABV62257.1};
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750 {ECO:0000313|EMBL:ABV62257.1, ECO:0000313|Proteomes:UP000001355};
RN [1] {ECO:0000313|EMBL:ABV62257.1, ECO:0000313|Proteomes:UP000001355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032 {ECO:0000313|EMBL:ABV62257.1,
RC ECO:0000313|Proteomes:UP000001355};
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
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DR EMBL; CP000813; ABV62257.1; -; Genomic_DNA.
DR RefSeq; WP_012010000.1; NZ_VEIA01000004.1.
DR AlphaFoldDB; A8FDE0; -.
DR STRING; 315750.BPUM_1575; -.
DR KEGG; bpu:BPUM_1575; -.
DR eggNOG; COG3173; Bacteria.
DR HOGENOM; CLU_078715_0_0_9; -.
DR OrthoDB; 334783at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR41283; AMINOGLYCOSIDE PHOSPHOTRANSFERASE; 1.
DR PANTHER; PTHR41283:SF1; APH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ABV62257.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:ABV62257.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..240
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 307 AA; 35598 MW; 5A101C05AF90283A CRC64;
MEYEKLKRLS PLLTQAISFQ LMTSGFSGNR TYLVTTSSSE KLVLKLSNLK TYSNFKRKAS
IQQKLKDRGL LCSEVMEIGM NTELNCTYRI FTFIEGENAR AAIHLLTNKE QYEIGRRAGE
ALSFMHTCPA PSHVTSWYER VMAKHERYVH AYRSSGVTFA QDQFVLDFIK SHADAVKARP
NQFQHDDFHL GNIIIQEGEY AGVIDFDQSD WGDPVHDFYK LSLFSRENSI PFSAGQLDHY
VSSQTTDDFW LLFSIYTAMS CFSSIVWTLS YDSEHVKDMV NRVERMLADH DYFHKLKPAW
YSNWHHS
//
