ID A8FGY8_BACP2 Unreviewed; 367 AA.
AC A8FGY8;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=AI-2E family transporter {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=BPUM_2850 {ECO:0000313|EMBL:ABV63505.1};
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750 {ECO:0000313|EMBL:ABV63505.1, ECO:0000313|Proteomes:UP000001355};
RN [1] {ECO:0000313|EMBL:ABV63505.1, ECO:0000313|Proteomes:UP000001355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032 {ECO:0000313|EMBL:ABV63505.1,
RC ECO:0000313|Proteomes:UP000001355};
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
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DR EMBL; CP000813; ABV63505.1; -; Genomic_DNA.
DR RefSeq; WP_012011116.1; NZ_VEIS01000008.1.
DR AlphaFoldDB; A8FGY8; -.
DR STRING; 315750.BPUM_2850; -.
DR KEGG; bpu:BPUM_2850; -.
DR eggNOG; COG0628; Bacteria.
DR HOGENOM; CLU_031275_8_2_9; -.
DR OrthoDB; 9793390at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF72; TRANSPORT PROTEIN YUEF-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 367 AA; 40490 MW; 529A32F101DD3EC0 CRC64;
MLKSKVHFWT FQILLVLLIV YVSTKVSFLF QPIILFASTL FVPILLAGIL FFIFNPIVRF
LSKKIPRTLA ILIIYLLFIG LITFIVNAAG PVIISQVGGL VKSFPGYVTD MQKFINDFSH
SKTFTWMMSQ DYVSVSKFEQ TVVSTLKALP ENIASSMSAV FGVIANIALA VITVPFILFY
MLKDGHKFPD KLVQFLPMPY RKEGLKIFKE LNDTLAAYIQ GQIIVCLFVG VACFIGYLLI
GVKYALILGI IIAVTNVIPY LGPYLGAAPA VLIAFLDSPG KAVVTVIVIL VVQQIDGNVI
SPLIIGKRLN THPLTIILLL IGAGSFGGIL GMIFAVPVYA LLKAITLNIV RLVQLRQRSR
KEQHLNV
//
