ID A8FHG3_BACP2 Unreviewed; 529 AA.
AC A8FHG3;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:ABV63680.1};
GN OrderedLocusNames=BPUM_3026 {ECO:0000313|EMBL:ABV63680.1};
OS Bacillus pumilus (strain SAFR-032).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=315750 {ECO:0000313|EMBL:ABV63680.1, ECO:0000313|Proteomes:UP000001355};
RN [1] {ECO:0000313|EMBL:ABV63680.1, ECO:0000313|Proteomes:UP000001355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAFR-032 {ECO:0000313|EMBL:ABV63680.1,
RC ECO:0000313|Proteomes:UP000001355};
RX PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA Weinstock G.M.;
RT "Paradoxical DNA repair and peroxide resistance gene conservation in
RT Bacillus pumilus SAFR-032.";
RL PLoS ONE 2:E928-E928(2007).
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DR EMBL; CP000813; ABV63680.1; -; Genomic_DNA.
DR RefSeq; WP_012011275.1; NZ_VEIS01000009.1.
DR AlphaFoldDB; A8FHG3; -.
DR STRING; 315750.BPUM_3026; -.
DR KEGG; bpu:BPUM_3026; -.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_025182_2_0_9; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000001355; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR031621; HisKA_7TM.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF16927; HisKA_7TM; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 306..358
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 387..520
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 529 AA; 61404 MW; ED38E0D227940B04 CRC64;
MDSIVLHFIV IMSVSGILSV ILSIIAHANR HRYIGCQLFM YMSGATAIYI FGHTFELLAS
TPREIMFWVC FQYIGLPFIA PFSLMIVLQF TGFHQYFTKR RVLLILLIPT LTTIMVFTNS
FHSLFYRSIT MNPVDGFLLA DFTIGYWYII HGVYTFGCSM LAIFMLVWFL RVTKKEYLKQ
ILILLVGMLL PITTSFIYLL GVTPLHIDPV PVVMFLTNAL YLWAIMSFQL FKLSPIAMER
VFEHMSEGVL ILDRYRTLID YNPAAASIIP SLSNKKGIGF KIDDIFSGFI KDHDFIQWLR
SPQDHSQYDL MLEREKDHSS YYHLTASSLF NRRGEVEGRQ IVISDVTEQR LLQEELERRA
YIDGLTNIFN RSSFIERTQM ILEEDAQDTA VMLFDIDFFK QINDTHGHHI GDEALRHVVT
ICQQHLQMDD LFGRYGGEEF AICLPHHSFE EACHIAERIR HSFEMSFFEN EEEKVRVTAS
FGIAHTAYDP NVLETLLFEA DQALYMSKRQ GRNRIYASTG ADYMLYEEN
//
