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Database: UniProt
Entry: A8G828
LinkDB: A8G828
Original site: A8G828 
ID   RHLB_SERP5              Reviewed;         428 AA.
AC   A8G828;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   16-OCT-2019, entry version 75.
DE   RecName: Full=ATP-dependent RNA helicase RhlB {ECO:0000255|HAMAP-Rule:MF_00661};
DE            EC=3.6.4.13 {ECO:0000255|HAMAP-Rule:MF_00661};
GN   Name=rhlB {ECO:0000255|HAMAP-Rule:MF_00661};
GN   OrderedLocusNames=Spro_0158;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DEAD-box RNA helicase involved in RNA degradation. Has
CC       RNA-dependent ATPase activity and unwinds double-stranded RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00661};
CC   -!- SUBUNIT: Component of the RNA degradosome, which is a multiprotein
CC       complex involved in RNA processing and mRNA degradation.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. RhlB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00661}.
DR   EMBL; CP000826; ABV39268.1; -; Genomic_DNA.
DR   RefSeq; WP_012004630.1; NC_009832.1.
DR   SMR; A8G828; -.
DR   STRING; 399741.Spro_0158; -.
DR   PRIDE; A8G828; -.
DR   EnsemblBacteria; ABV39268; ABV39268; Spro_0158.
DR   KEGG; spe:Spro_0158; -.
DR   eggNOG; ENOG4105C1J; Bacteria.
DR   eggNOG; COG0513; LUCA.
DR   HOGENOM; HOG000268807; -.
DR   KO; K03732; -.
DR   OMA; TRFHDFK; -.
DR   OrthoDB; 626183at2; -.
DR   Proteomes; UP000007074; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00661; DEAD_helicase_RhlB; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR023554; RNA_helicase_ATP-dep_RhlB.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; RNA-binding.
FT   CHAIN         1    428       ATP-dependent RNA helicase RhlB.
FT                                /FTId=PRO_1000082855.
FT   DOMAIN       40    219       Helicase ATP-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   DOMAIN      245    390       Helicase C-terminal. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   NP_BIND      53     60       ATP. {ECO:0000255|HAMAP-Rule:MF_00661}.
FT   MOTIF         9     37       Q motif.
FT   MOTIF       165    168       DEAD box.
SQ   SEQUENCE   428 AA;  47879 MW;  C8218430BEDF0F33 CRC64;
     MSKTHLTEQK FSDFALHPLV LEALEKKGFQ HCTPIQALAL PLTLSGRDVA GQAQTGTGKT
     LAFLTSTFHY LLSHPAKQDR KINQPRALIM APTRELAVQI HSDAEALSQS TGLKMGLAYG
     GDGYDKQLKV LESGVDILVG TTGRLIDYAK QNYIDLGAIQ VVVLDEADRM YDLGFIKDIR
     WLFRRMPAVD QRLNMLFSAT LSYRVRELAF EQMNNAEYVE VEPEQKTGHR IKEELFYPSN
     EEKMRLLQTL IEEEWPDRCI IFANTKHRCE DVWGHLAADG HRVGLLTGDV AQKKRLRILD
     DFTKGNLDIL VATDVAARGL HIPLVTHVFN YDLPDDCEDY VHRIGRTGRA GESGHSISLA
     CEEYALNLPA IETYTGHSIP VSKYNSDALL SDLPAPKRLA RPRGGNGPRR NSAPRRGGAP
     RNNRKRSG
//
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