ID A8GCH5_SERP5 Unreviewed; 737 AA.
AC A8GCH5;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:ABV40815.1};
GN OrderedLocusNames=Spro_1711 {ECO:0000313|EMBL:ABV40815.1};
OS Serratia proteamaculans (strain 568).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=399741 {ECO:0000313|EMBL:ABV40815.1};
RN [1] {ECO:0000313|EMBL:ABV40815.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=568 {ECO:0000313|EMBL:ABV40815.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA Vangronsveld J., van der Lelie D., Richardson P.;
RT "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000826; ABV40815.1; -; Genomic_DNA.
DR AlphaFoldDB; A8GCH5; -.
DR STRING; 399741.Spro_1711; -.
DR KEGG; spe:Spro_1711; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_0_6; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 491..672
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 737 AA; 83033 MW; B82EF7C04222E10D CRC64;
MPYLPDVRIA LWVILPVCLC LWGRGCAGRF MAWGALGFLW AVFSAGTLVN QINRLSQGPV
VSAVVQVSSI ALAGATRKQT VMRIERLNGR WLVPSIAFST LWKPKDRSLC AGQRWQLQLR
LRPIHGNLNE GGFDRQRWAM SQRQPLTAQV KSAVILEQNC GWRQRMIAHA ENNIGTLRYK
TVLLALAFGE RAALEPALRT LMLKTGIAHL MAISGLHVAM VAILIWGVLR AMQFFLPARL
IGYRFPLIVS WLGALGYVWL AGAHPPALRT GLALTLWMLL RIRGIHCSSW QIWLWCVGLI
LICDPLAVLS DSFWLSATAV FCLIFWFEWV PLNLRFRSGW HWAPLRWLHI QLGITLLLLP
MQAGLFHGLT LGSIPANLWA VPLVSLITVP LILLAVVAGI FPVLSAGLWR LADFTLAGVF
TPLHYLQIGW VDLGAASLAV SLAGWLLVIF WRFHWWLRYA TALVTLALCC VLWREREAQY
RWRVDMLDVG HGLAMVIEKN GRAILYDTGP RWGTGSAAGR NILPFLNWRG LPVEEIILSH
DHLDHIGGIE EIQRAFPQAR VRSPRLNAGH LPCVAGERWQ WQSLQFQVLW PPKAVKLAGN
DDSCVIRIDD GKYSLLLTGD AEKRTEAQLV RYQRPSLSAT VLQVPHHGSK TSSTPPFLRA
VAPKAAIASA SRYNKWRLPA VKVVARYLAN DILWHDTSRS GQLSVLFFDN DWQINGFREQ
LMPRWYHQRF GVEGDNE
//
