ID A8GFH1_SERP5 Unreviewed; 573 AA.
AC A8GFH1;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN OrderedLocusNames=Spro_2760 {ECO:0000313|EMBL:ABV41861.1};
OS Serratia proteamaculans (strain 568).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=399741 {ECO:0000313|EMBL:ABV41861.1};
RN [1] {ECO:0000313|EMBL:ABV41861.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=568 {ECO:0000313|EMBL:ABV41861.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA Vangronsveld J., van der Lelie D., Richardson P.;
RT "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; CP000826; ABV41861.1; -; Genomic_DNA.
DR AlphaFoldDB; A8GFH1; -.
DR STRING; 399741.Spro_2760; -.
DR KEGG; spe:Spro_2760; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_9_6; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABV41861.1}.
FT DOMAIN 40..430
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 480..554
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 573 AA; 63888 MW; 4250C52652BAEF21 CRC64;
MIMNNDFRSN TLDKVWLKRY PADVPAEIDA DRYSSLVEMF ENAVKRYADQ PAFMNMGEVM
TYRKLEERSR AFAAYLQNEL GLQKGDRVAL MMPNLLQYPI ALFGILRAGM VVVNVNPLYT
PRELEHQLND SGASAIVIVS NFAHTLEKVV FNTQIKHVIL TRMGDQLSAA KGTLVNFVVK
YIKRLVPKYH LPAAISFRSA LQRGRRLQYV KPDIINSDLA FLQYTGGTTG VAKGAMLTHR
NMQANLEQAK AAYLPLFREG QELVVTALPL YHIFALTVNC LLFIDLGGHN LLITNPRDIP
GLVKELGKYP FTAMSGVNTL FNALLNNEDF HKLDFSTLRF SVGGGMSVQK AVAEKWEKTT
GKHLLEGYGL TECAPLVTGN PYDLKHYSGS IGLPVPSTDI RLVDDNGHDV PVGEPGELWV
KGPQVMLGYW QRPDATDEVL KDGWLATGDI VTVDEMGFVR VVDRKKDMIL VSGFNVYPNE
IEDVVSQHPK VLECAAIGVP SDVSGEAVKI CVVKKDASLT KEELLTHCRR QLTGYKVPKI
VEFRDELPKS NVGKILRREL RDEQKKPVAA DAA
//
