ID A8GZE9_SHEPA Unreviewed; 372 AA.
AC A8GZE9;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ABV85686.1};
GN OrderedLocusNames=Spea_0358 {ECO:0000313|EMBL:ABV85686.1};
OS Shewanella pealeana (strain ATCC 700345 / ANG-SQ1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=398579 {ECO:0000313|EMBL:ABV85686.1, ECO:0000313|Proteomes:UP000002608};
RN [1] {ECO:0000313|EMBL:ABV85686.1, ECO:0000313|Proteomes:UP000002608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700345 / ANG-SQ1 {ECO:0000313|Proteomes:UP000002608};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C.,
RA Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Zhao J.-S.Z., Manno D., Hawari J., Richardson P.;
RT "Complete sequence of Shewanella pealeana ATCC 700345.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP000851; ABV85686.1; -; Genomic_DNA.
DR RefSeq; WP_012153627.1; NC_009901.1.
DR AlphaFoldDB; A8GZE9; -.
DR STRING; 398579.Spea_0358; -.
DR KEGG; spl:Spea_0358; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_2_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000002608; Chromosome.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.1990; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF11; BLL4320 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002608}.
FT DOMAIN 55..269
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 372 AA; 40618 MW; 2BBAF7025976397D CRC64;
MKKWTLVMII IAVLAFGSVI GFNLFIKGKI ADAIANMPEA VAPVTAIDIK ESKWQPTINA
IGFVEPNQGV SIANEVAGVV SAIRFENGSQ VQAGQMLVEL DSKVEKANLK SKQVQLPAAE
ADYKRLSKLY KQNSISKQDL DNSQSKYLAL MADIESLSAT IDRREIKAAF TGLVGIRNVN
LGEYLQTGTD IVRLEDISTM KIRFTIPQTQ LPRIETGQVV HVHVDAYPTE PFEGTISAIE
PAVFYQSGLI QVQALIPNSH GKLRSGMFAK VDIMLPELTQ QVVLPQTAIS FTLYGDSVYV
IEEKNEDGEQ VKRVKQVNVK VLERDDINAL ITGGVNAGDT IVTSGQVRLS NNTKVKVTED
DALTPPATLP QL
//
