ID A8H9J9_SHEPA Unreviewed; 225 AA.
AC A8H9J9;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=Spea_3926 {ECO:0000313|EMBL:ABV89236.1};
OS Shewanella pealeana (strain ATCC 700345 / ANG-SQ1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=398579 {ECO:0000313|EMBL:ABV89236.1, ECO:0000313|Proteomes:UP000002608};
RN [1] {ECO:0000313|EMBL:ABV89236.1, ECO:0000313|Proteomes:UP000002608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700345 / ANG-SQ1 {ECO:0000313|Proteomes:UP000002608};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C.,
RA Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Zhao J.-S.Z., Manno D., Hawari J., Richardson P.;
RT "Complete sequence of Shewanella pealeana ATCC 700345.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP000851; ABV89236.1; -; Genomic_DNA.
DR RefSeq; WP_012157117.1; NC_009901.1.
DR AlphaFoldDB; A8H9J9; -.
DR STRING; 398579.Spea_3926; -.
DR KEGG; spl:Spea_3926; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_2_0_6; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000002608; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002608};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 22..223
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 225 AA; 24299 MW; 0BC80F20E4BC8045 CRC64;
MNVLMVLTSH DKLGDTGLKT GFWLEEFASP FYRFKDCGFT ITLASPAGGQ PPLDPSSEQP
DFQTAATERF NQDGQAKQQL ATTKVLAEIN QADYDAIFYP GGHGPLWDLT NDVHSIALIE
AFYQAQKPVG LVCHAPGALK NVKAADGTPL VAGKRVTGFT NSEESAVQLT EIVPFLVEDM
LQQNGALYSK GDDWSSYLAV DGNLITGQNP ASSEAVANEI IKQFK
//
