ID A8KYM0_FRASN Unreviewed; 470 AA.
AC A8KYM0;
DT 04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT 04-DEC-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Glutamate--putrescine ligase {ECO:0000313|EMBL:ABW10116.1};
DE EC=6.3.1.11 {ECO:0000313|EMBL:ABW10116.1};
GN ORFNames=Franean1_0657 {ECO:0000313|EMBL:ABW10116.1};
OS Frankia sp. (strain EAN1pec).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW10116.1};
RN [1] {ECO:0000313|EMBL:ABW10116.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EAN1.pec {ECO:0000313|EMBL:ABW10116.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Kim E., Rawnsley T., Niemann J., Benson D.R., Huang Y.,
RA Mastronunzio J., Bassi C.A., Tisa L.S., Richardson P.;
RT "Complete sequence of Frankia sp. EAN1pec.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01331, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; CP000820; ABW10116.1; -; Genomic_DNA.
DR AlphaFoldDB; A8KYM0; -.
DR STRING; 298653.Franean1_0657; -.
DR KEGG; fre:Franean1_0657; -.
DR eggNOG; COG0174; Bacteria.
DR HOGENOM; CLU_017290_0_3_11; -.
DR GO; GO:0034024; F:glutamate-putrescine ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF16; GLUTAMINE SYNTHETASE GLNA4 (GLUTAMINE SYNTHASE) (GS-II)-RELATED; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:ABW10116.1}.
FT DOMAIN 138..470
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 50831 MW; FB0BF601927FBBA5 CRC64;
MTPEPDHTRA DGTRADHTQA DDTPEHPGLA TLLGDVDEVI VAVPDLQGRL VGTGLSPEYF
REEVLGGDGL GACAYLHAVD VEMETGPGYA YDPWEGGFGD LRLVPDLSTL GHAPWHPESA
IVIADAVWPD GTPVDVAPRT VLRRQLDRLA ALGLRALAGT ELEFLVFEEA YRKAAGRDYA
RLTPASSYNV DYALAGTERM DDLVRSIRRA MAAAGAPVES ARAEVHPGQY EIVFRYDEAL
RTCDRHALYK TTAKKIAGTA GRALTFMAKY DQGEGNSCHV HLSLRAADGG FVLSAGAEEG
MSELMRWFVA GQLACMAELT LLYAPTVNSY KRLAPGGFAP TGISWGLDNR TCAIRVVGRG
RSLRIEHRVP GGDANPYLAI AGMLAAGLHG IENRLPLPPP RAGNVFAAPD VPRLPASLRD
AARAWRESAT ARAAFGERVV DHLAHAADVE LAGYERTVTD WERRRGFERY
//
