ID   A8LP02_DINSH            Unreviewed;       422 AA.
AC   A8LP02;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Cytosine deaminase {ECO:0000313|EMBL:ABV93684.1};
DE            EC=3.5.4.1 {ECO:0000313|EMBL:ABV93684.1};
GN   Name=codA {ECO:0000313|EMBL:ABV93684.1};
GN   OrderedLocusNames=Dshi_1943 {ECO:0000313|EMBL:ABV93684.1};
OS   Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Dinoroseobacter.
OX   NCBI_TaxID=398580 {ECO:0000313|EMBL:ABV93684.1, ECO:0000313|Proteomes:UP000006833};
RN   [1] {ECO:0000313|Proteomes:UP000006833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16493 / NCIMB 14021 / DFL 12
RC   {ECO:0000313|Proteomes:UP000006833};
RX   PubMed=19741735; DOI=10.1038/ismej.2009.94;
RA   Wagner-Dobler I., Ballhausen B., Berger M., Brinkhoff T., Buchholz I.,
RA   Bunk B., Cypionka H., Daniel R., Drepper T., Gerdts G., Hahnke S., Han C.,
RA   Jahn D., Kalhoefer D., Kiss H., Klenk H.P., Kyrpides N., Liebl W.,
RA   Liesegang H., Meincke L., Pati A., Petersen J., Piekarski T.,
RA   Pommerenke C., Pradella S., Pukall R., Rabus R., Stackebrandt E., Thole S.,
RA   Thompson L., Tielen P., Tomasch J., von Jan M., Wanphrut N., Wichels A.,
RA   Zech H., Simon M.;
RT   "The complete genome sequence of the algal symbiont Dinoroseobacter shibae:
RT   a hitchhiker's guide to life in the sea.";
RL   ISME J. 4:61-77(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000830; ABV93684.1; -; Genomic_DNA.
DR   RefSeq; WP_012178613.1; NC_009952.1.
DR   AlphaFoldDB; A8LP02; -.
DR   STRING; 398580.Dshi_1943; -.
DR   KEGG; dsh:Dshi_1943; -.
DR   eggNOG; COG0402; Bacteria.
DR   HOGENOM; CLU_031758_0_1_5; -.
DR   OrthoDB; 9815027at2; -.
DR   Proteomes; UP000006833; Chromosome.
DR   GO; GO:0102480; F:5-fluorocytosine deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004131; F:cytosine deaminase activity; IEA:UniProtKB-EC.
DR   CDD; cd01293; Bact_CD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR013108; Amidohydro_3.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR32027; CYTOSINE DEAMINASE; 1.
DR   PANTHER; PTHR32027:SF0; CYTOSINE DEAMINASE; 1.
DR   Pfam; PF07969; Amidohydro_3; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABV93684.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006833}.
FT   DOMAIN          39..399
FT                   /note="Amidohydrolase 3"
FT                   /evidence="ECO:0000259|Pfam:PF07969"
SQ   SEQUENCE   422 AA;  45772 MW;  173876A79DF27657 CRC64;
     MVDILVKGGT LPDGTQADIA ITGDRIVDVA PGIAAKAGEV IDATGDLVSP PFVDPHFHMD
     ATLSYGIPRI NASGTLLEGI ALWGELKHET TIDAMIDRAL RYCDWAVSMG LLAIRSHVDT
     CDDSLKGVQA MLQLRETVKP YLDLQLVAFP QDGLYRDPTA RENTLRALDM GLDVVGGIPH
     FERTMADGAA SVRDLCEIAA DRGLPVDMHC DESDDPMSRH IETLAAETVR CGLQGRVAGS
     HLTSMHSMDN YYVSKLLALV AEAGISAIPN PLINIMLQGR HDTYPKRRGL TRVREMQALG
     IPVGWGQDCV RDPWYSLGTA DMLDVAFMGL HVAQMSAPEE MARCFEMVTE TNAAIIGLPD
     YGLRKGALAS LVVLDAADPI EAVRLRPDRL CVISKGRVVS RKARNDAALT LPGRPATVHR
     RH
//