ID IQCF6_HUMAN Reviewed; 107 AA.
AC A8MYZ5;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-FEB-2014, sequence version 3.
DT 24-JAN-2024, entry version 90.
DE RecName: Full=IQ domain-containing protein F6;
GN Name=IQCF6;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
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DR EMBL; AC099050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS54590.1; -.
DR RefSeq; NP_001137305.2; NM_001143833.3.
DR RefSeq; XP_011532030.1; XM_011533728.1.
DR AlphaFoldDB; A8MYZ5; -.
DR SMR; A8MYZ5; -.
DR STRING; 9606.ENSP00000381760; -.
DR GlyGen; A8MYZ5; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; A8MYZ5; -.
DR PhosphoSitePlus; A8MYZ5; -.
DR BioMuta; IQCF6; -.
DR MassIVE; A8MYZ5; -.
DR PaxDb; 9606-ENSP00000381760; -.
DR PeptideAtlas; A8MYZ5; -.
DR ProteomicsDB; 2439; -.
DR Antibodypedia; 71165; 28 antibodies from 10 providers.
DR DNASU; 440956; -.
DR Ensembl; ENST00000398780.5; ENSP00000381760.3; ENSG00000214686.7.
DR GeneID; 440956; -.
DR KEGG; hsa:440956; -.
DR UCSC; uc021wyv.1; human.
DR AGR; HGNC:35158; -.
DR CTD; 440956; -.
DR GeneCards; IQCF6; -.
DR HGNC; HGNC:35158; IQCF6.
DR HPA; ENSG00000214686; Tissue enriched (testis).
DR neXtProt; NX_A8MYZ5; -.
DR OpenTargets; ENSG00000214686; -.
DR VEuPathDB; HostDB:ENSG00000214686; -.
DR eggNOG; ENOG502TCZB; Eukaryota.
DR GeneTree; ENSGT00390000004641; -.
DR HOGENOM; CLU_114989_1_0_1; -.
DR InParanoid; A8MYZ5; -.
DR OrthoDB; 4641637at2759; -.
DR PhylomeDB; A8MYZ5; -.
DR TreeFam; TF337908; -.
DR PathwayCommons; A8MYZ5; -.
DR SignaLink; A8MYZ5; -.
DR BioGRID-ORCS; 440956; 9 hits in 1071 CRISPR screens.
DR GenomeRNAi; 440956; -.
DR Pharos; A8MYZ5; Tdark.
DR PRO; PR:A8MYZ5; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; A8MYZ5; Protein.
DR Bgee; ENSG00000214686; Expressed in male germ line stem cell (sensu Vertebrata) in testis and 36 other cell types or tissues.
DR ExpressionAtlas; A8MYZ5; baseline and differential.
DR Genevisible; A8MYZ5; HS.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR Gene3D; 1.20.5.190; -; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR039887; IQCF.
DR PANTHER; PTHR21633:SF15; IQ DOMAIN-CONTAINING PROTEIN F6; 1.
DR PANTHER; PTHR21633; IQ MOTIF CONTAINING F; 1.
DR Pfam; PF00612; IQ; 2.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW Reference proteome; Repeat.
FT CHAIN 1..107
FT /note="IQ domain-containing protein F6"
FT /id="PRO_0000343226"
FT DOMAIN 42..71
FT /note="IQ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
SQ SEQUENCE 107 AA; 13059 MW; 4B822CE61AA52CDA CRC64;
MVRRTLLQAA LRAWVIQCWW RSMQAKMLEQ RRRLALRLYT CQEWAVVKVQ AQVRMWQARR
RFLQARQAAC IIQSHWRWHA SQTRGLIRGH YEVRASRLEL DIEILMT
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