ID A8N8X8_COPC7 Unreviewed; 1103 AA.
AC A8N8X8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Transcription factor BYE1 {ECO:0000256|ARBA:ARBA00021616};
GN ORFNames=CC1G_00853 {ECO:0000313|EMBL:EAU90469.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU90469.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU90469.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- FUNCTION: Negative regulator of transcription elongation.
CC {ECO:0000256|ARBA:ARBA00002311}.
CC -!- SIMILARITY: Belongs to the BYE1 family.
CC {ECO:0000256|ARBA:ARBA00011050}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU90469.1}.
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DR EMBL; AACS02000007; EAU90469.1; -; Genomic_DNA.
DR RefSeq; XP_001831306.1; XM_001831254.1.
DR AlphaFoldDB; A8N8X8; -.
DR STRING; 240176.A8N8X8; -.
DR GeneID; 6007777; -.
DR KEGG; cci:CC1G_00853; -.
DR VEuPathDB; FungiDB:CC1G_00853; -.
DR eggNOG; KOG1634; Eukaryota.
DR InParanoid; A8N8X8; -.
DR OMA; AWISCET; -.
DR OrthoDB; 5491784at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd21538; SPOC_TFIIS; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF20; PROTEIN PARTNER OF SNF, ISOFORM B; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 256..404
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1083
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1103 AA; 120871 MW; 1054BC4F2AFDA830 CRC64;
MATRSKAKAA ASATGKKAAQ QSSKRAKTET SSSARASEER SVNGRRKPSK TAPAKRAKPK
PDASVKEEYC TCSKGDDGSP MVVCGQCKIW YHFVCVDLAE KDAEDICFYV CPTCTTSTGL
RTTRSWEGRV AFDDPNEAAI SKGPVAPSKR KTSKPPVAKK PMSDESDNEV SSEDDFVMEE
EEKKPQVAQA KRRRTAVASD TDTDTSDSDA HIKRKRRLRR VSASPAPNTM KRKASVSQAP
TPVKRSKSTP PQEDPTRKYC LGKLQELFRD IFFRYPHIQT PEGTLVAKAV DEMTEEEKDA
LTQEANQFAH DLEMCIFEIY AEPDKNGNPN AGMKYKDRFR TLQFNLSKHD RVVIHQRITS
RNIAPKELSQ MSSTDLANEE TKQLIKVAEK EALEHSILPQ ITAPRAKITH KGIEDIEVDD
DDPSTSTLDY EQDQKERERV AEERRERERM ARLRGVQRQR TASMSVPPES PTVLQTPTSD
SWGAPPPVPA HAQSPVQESG GQSALPPLAL AGSEIRYTPE PELNLSDLIN IDEEATPSSE
AVPTPPTTST QGDQATRVDP FSRPIITVPS SSSDPPTDES PSVTAVPPEK PGFNLSTLWT
TNATDKEKDA DMDDNDDGEP MAISPPPLSP PALHDDDDKD ILAEGGDNMD GPEPDFDALF
QEQPPEPPRP QVPVSVEQIP QVWTGKLSMP LDSSIPQDTP MVARQVAGTT IEPESLLWKT
LFPSDHLGIG GRVPIANSSD YLTQMRLNPT KELYAVAFAP ASEQDEASFQ ALSDFLVAKG
RHGLIFPWGQ RPKEHHPGKE LYIIPLKASE PIPEYMELLD NLKIPKERKR NYLIGIWVLN
KGKLAPPPPP PPVAAPVSMT LSVAHQPTPP TVPAAPVNVT ATPPHIPPIA SPAIPLGSST
PLGVPPTPVN PILPINGPLP PGVDPVALAA EVASLTPEQL QLLRSLAGSA IPVPSQPPQQ
APAAVPVPPA FPPYPPPPAV PTMPPDHLRH TWQGSASPYT PPQYQGYGDH GAANHASQPH
RPPPPPHNYP NDRYDAHGHH QGHGDREHHR GGWRGKNKSR GHWDRNQGHR DQQHRDNYRP
VDSGWPRKQH GAGEQSYGHG RQW
//
