ID A8NG37_COPC7 Unreviewed; 1508 AA.
AC A8NG37;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Sec7 domain-containing protein {ECO:0000313|EMBL:EAU88400.2};
GN ORFNames=CC1G_05166 {ECO:0000313|EMBL:EAU88400.2};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU88400.2, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU88400.2, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU88400.2}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACS02000002; EAU88400.2; -; Genomic_DNA.
DR RefSeq; XP_001833466.2; XM_001833414.2.
DR STRING; 240176.A8NG37; -.
DR GeneID; 6009962; -.
DR KEGG; cci:CC1G_05166; -.
DR VEuPathDB; FungiDB:CC1G_05166; -.
DR eggNOG; KOG0928; Eukaryota.
DR HOGENOM; CLU_001204_3_1_1; -.
DR InParanoid; A8NG37; -.
DR OMA; CRDIRHH; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001861}.
FT DOMAIN 583..775
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 242..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1508 AA; 166978 MW; 48D7DBDE24B93799 CRC64;
MTSSTSSRTG TSLRHVIQAE ILSVTSTMRR NSRWASSTVV IGHRGHPREL GSDLGLRLSS
PAAPVHQSGR GSKEAELMAN FVELQRTIQN IPDVAVLDLG TLLAPFLAII RSPLSTGPIT
SSALSALHSF FVCGIIRPDA SEHLNVVLAE LSNTISHCRF EASDSSGDEV VLLKLMTVIE
DFICNPVGGS LGDVEVCELL EAVLTTCCQP RLSGTLRRSA ENTMHNLVRT VFRKLNQLDP
ETEEAKLKSD EAETEGELKM TVQSSTEAVQ ETQTEEPVEG SPEATNASEA PASEQDQGQE
NQPQQQPEQP SSTTVPQEEE EPTSAVSFGK KPEYGLPSLI ELLRVIINVL DPTAQQHTDS
IRLIALGILN AAFDEAGCTI SKFPSLRVLI TDPGCKYLFQ LARSENNAIL HLSLRTIFTI
LDCMKKDLKL QQELLLTFTI DRLYLPPARL QVPARRGATS SPRPGTPSIA TPPLGPSDEK
ADTPRRVPPA RGEIRDYILE TLSHLVHQPN FMVDIYANYD CDTNCENLFE KLIEFLTKAV
YPAQGLTSLE SQRNTQYLCL EMLLAFVNDM ANRANANTDA IHSLLQAKSR KELISAGATK
FNTKPKTGVA FLEENGFIYQ DLSPEVSKPQ SLAKFLKSCG RLDKRVLGGY ISKPDNIELL
KAFIGLFDFK GKDVADALRD MLEAFRLPGE SQQISRITEV FSSIYFATGP EEIKSEDACY
VLAYSVIMLN TDLHNAQVRK RMSVEDYKKN LRGVNEKTDF SSEYLTKIYE SIKKEEIVMP
EEHSGQVGFE YAWKELLTRS RQAGDFVQYN TSVFDVEMFK AVWKPVISAI AYAFITFDDD
YIIQRAVAGF RQCATLAGRF NLPDVFDFVV ISLSQATGLL SESLPAQVPN YPIVEVEGQS
VTVSKLSVEF GTNFKGQLAA VVLFNIVNGN GNALREGWTQ IFEMFQNLFL HSLLPTRMLQ
MEDFLGGFTM IPLRGSQPQP AQSRGDGGLL STLSSYLMTP YSSSEAQVPD ATDADVENTL
CTIDCITSCR LDEFYSQITQ IDSDAMVAAV RALEALAHER TVAKLRLHSE DNLTALDDPP
YKLPYDPASV FLLETMASIA CQAPQFIEEL WPVIFEHISA LLSSAAQYSI LLIERAVVCL
LRLCQILAYN PSLRDQIYVS LDLLARIHPS VSSSVGDQVV AGLIVIMQKH PNIVRSQTEW
NLVFALLRNM LSHPEAARLT FELTSNLAGE GPDADVSLDN FAGLVTILDD FASAAGALVE
AHTRQSRRRV EPLTAANSVP VERGKKSVEY IAAMLKRLPE LLTQAQVAPP EAWKHFTLPL
LSSLARQSVN ASREIRHVAI SQLQRILLGP ALDPGTTDQS QVEDVFNRVV FPLIDDLLKP
QVYQRDPQGM SETRLRASAL LCKSFMHLEV REEKMRTDFR LLWIQILDLL DRLMIAGRDD
QLNEAVPESL KNVLLVMNAV GILVPPAPEG EEQDQLRKTL WTATHERLER FLPGFLQSVI
APPQAPIP
//
