ID A8NI04_COPC7 Unreviewed; 1035 AA.
AC A8NI04;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Importin-13 {ECO:0000256|ARBA:ARBA00016020};
GN ORFNames=CC1G_01550 {ECO:0000313|EMBL:EAU87903.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU87903.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU87903.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- SIMILARITY: Belongs to the importin beta family.
CC {ECO:0000256|ARBA:ARBA00007991}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU87903.1}.
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DR EMBL; AACS02000010; EAU87903.1; -; Genomic_DNA.
DR RefSeq; XP_001833873.1; XM_001833821.1.
DR AlphaFoldDB; A8NI04; -.
DR STRING; 240176.A8NI04; -.
DR GeneID; 6010377; -.
DR KEGG; cci:CC1G_01550; -.
DR VEuPathDB; FungiDB:CC1G_01550; -.
DR eggNOG; KOG2022; Eukaryota.
DR InParanoid; A8NI04; -.
DR OMA; CLASIGK; -.
DR OrthoDB; 7225at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR040709; Importin_rep_1.
DR InterPro; IPR040520; Importin_rep_3.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR PANTHER; PTHR12363:SF33; TRANSPORTIN-3; 1.
DR Pfam; PF18773; Importin_rep; 1.
DR Pfam; PF18806; Importin_rep_3; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 113..258
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
SQ SEQUENCE 1035 AA; 113169 MW; 0636AA5345FBEFAB CRC64;
MANIDFLPSL SALDVERAAQ LIQHAHGPST STTSPEDLKR LQQELFEMQK RPEAWGLVIP
FLNHDDQNVQ FFGAHTAQVK IARDWDMFPN EHAEGLKDLL VQLTAHSAAA GRPNFILRKL
FVAVTSLALK LAPGHPSRWP SWIISCVNQF SAVGVAPERI HQFLTIVAEE VGGADLLGPS
KMQMQQSLLD ATPMVVQAIT ASISQPKGAV PISQVQSSLQ TLQAWMTIFP ANDLVPFIPI
LISLLDPSED NEQAFCVASE TLQEVLSKSP LSEGAGSKAL TEPLLLWMDS VGSSVVKTMI
DKGEVDEFAH SVCKLLVALG DHSAPYIAAN IASPAPVTPD RSRAQLVQTF LRLMLAYTGL
PGYYGVDEEE SELTLGFWYL FQEALWSTDY YFEENGDDDS IQPPSRKDPV QVEMANAVYS
ELVQVLRRKA AFPTPPSGWS KDQLEKFNVY RRDIGDTLIN AYYVLKDNML SYYIDDMVQR
MAVESPNWQD IESNLHCIMS VQEAVDLDNA PQLARLFSSD VLGRLPTTGH NRLRRTTLSL
IGSYSTWFPS YMKSTSIPVD SNLLMNVLNY VVTALSDQAL CLQAATAFRN ICDANRKALA
PHISAFGQLH DNLDNIPDSE RSKVLQSIAS VIQALPPAEM IPPVEVIVSP IVQKLVAAIQ
NSATLPEEAR SVVILQLEIL SGVAKGLTRA NEGLYSEDED DPAIKAELDK IKAAREDPRM
HKLREDIFLS IGKIVEIWST DAEISHALSD LFKSITSLPS DMTLLSLTAG PLLQLISVAA
QRQLTATWLS LSTILIAQLN PPSYSLLTKA VPGKDAETTV ANVLPILLQC GLTMLGGPGA
MESNPDIVQE FFSCMDRVAQ DFTKSFYALP PGMLDLLMQC AISALALQER YSLVSACNFM
SNLIHRSSLT SELSTHKNNL LMAHGRAITS AVLHGIAGVA PRSVVPNLIE MLGTLMNRSS
GLEGGPAIVG RWMQEILFSG DFVQTKAGAE TKDKFIKAVI ASRSLKKTRD AAQQFALVAR
GLEGSSFGYA SVVAM
//
