ID A8NVE2_COPC7 Unreviewed; 516 AA.
AC A8NVE2;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 2 {ECO:0000313|EMBL:EAU85239.1};
GN ORFNames=CC1G_06255 {ECO:0000313|EMBL:EAU85239.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU85239.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU85239.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU85239.1}.
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DR EMBL; AACS02000004; EAU85239.1; -; Genomic_DNA.
DR RefSeq; XP_001836668.1; XM_001836616.2.
DR AlphaFoldDB; A8NVE2; -.
DR STRING; 240176.A8NVE2; -.
DR GeneID; 6013216; -.
DR KEGG; cci:CC1G_06255; -.
DR VEuPathDB; FungiDB:CC1G_06255; -.
DR eggNOG; KOG2667; Eukaryota.
DR InParanoid; A8NVE2; -.
DR OMA; WGWPDHE; -.
DR OrthoDB; 8790at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046907; P:intracellular transport; IEA:UniProt.
DR InterPro; IPR045888; Erv.
DR InterPro; IPR012936; Erv_C.
DR InterPro; IPR039542; Erv_N.
DR PANTHER; PTHR10984; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; 1.
DR PANTHER; PTHR10984:SF30; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2; 1.
DR Pfam; PF07970; COPIIcoated_ERV; 1.
DR Pfam; PF13850; ERGIC_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..106
FT /note="Endoplasmic reticulum vesicle transporter N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13850"
FT DOMAIN 161..327
FT /note="Endoplasmic reticulum vesicle transporter C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07970"
FT REGION 372..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..438
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 55869 MW; A4735A9D73432120 CRC64;
MGGLALFLAK LEDAIPASLT KFDAFPKLPS TYKARSESRG FLMVFVIILA FLLMLNDIGE
FIWGWPDFEF GVDNDKGSTL PINLDMTVNM PCKYLTVDLR DAMGDRLFLS NGFRRDGTIF
DVGQATALKE HAAALSAQEA VAQSRKSRGF FATLFRSKKS KFKPTYNHQA DASACRIWGT
MYVKKVTANL HVTTLGHGYA SYEHVDHHLM NLSHVIQEFS FGPHFPEIVQ PLDNSFEATH
EHFIAYQYFL HVVPTTYVAP RTAPLETNQY SVTHYTRVLE HNRGTPGIFF KFELDPLKIT
QYQRTTTLLQ LMIRCVGVIG GVFVCTSYAL RIGTRAVEVV SGADQKAGIV AAESTAVKVG
LRAKWGGSDL RARPGAVNRS LSSGSWTPSS PYGGFPATTP VTGTYSAMPS PYLSSNHAIP
SQPGTPNPAT PGYPVPPTPG GIRTAASMGP PPRTPSSAYP ASPYLATGGP TDGGASVPPT
PGYQYATFPT SPHPTNGNGL HPPPPPRKNT GGPKDD
//
