ID A8P2J4_COPC7 Unreviewed; 604 AA.
AC A8P2J4;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CC1G_04780 {ECO:0000313|EMBL:EAU83524.2};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU83524.2, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU83524.2, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU83524.2}.
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DR EMBL; AACS02000013; EAU83524.2; -; Genomic_DNA.
DR RefSeq; XP_001838336.2; XM_001838284.2.
DR AlphaFoldDB; A8P2J4; -.
DR STRING; 240176.A8P2J4; -.
DR GeneID; 6014918; -.
DR KEGG; cci:CC1G_04780; -.
DR VEuPathDB; FungiDB:CC1G_04780; -.
DR eggNOG; KOG2084; Eukaryota.
DR HOGENOM; CLU_018406_4_1_1; -.
DR InParanoid; A8P2J4; -.
DR OMA; CSHRERF; -.
DR OrthoDB; 166337at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12197:SF251; EG:BACR7C10.4 PROTEIN; 1.
DR PANTHER; PTHR12197; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 60..350
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 106..146
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..530
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 64969 MW; 99BBEA683605B553 CRC64;
MSDFRTLKSS RATRQSFVKA EKKPENETGI QSEISQKVES EPQLGSSYTP ADGLYSSLPS
SLQIRVEPET GRGIYTTDNG FKPGAVLVST KPHIATLSTS QLSSYCSACF GPGTSAPLKR
CPNCKIVMYC GSACQSRDWS LHKLECSALQ RWMSQPRPQP PPGSSSEPQV VSSGETRAPP
SDAIRTLARI LWRKQKVGLT STWAKEIDLL QSHRASLSKP TVSQSPTSND ASSNITKAAE
LHTHLSHGLI HYMGLTSPQE LEPYGINSAG DLVDLLSRFT TNTFTLTSPS LTPLGACISP
VAALFNHSCD PNAVIVFPRP LGDKKEHEPL LQIIAIKPIP PNTQASQEGL EKAERIQGSD
PQKALHLTRN LVPLLTSAGL VPSAHPLLAL TGLHTQFLID ELSPILASLP SLNTSPRDIN
DKMDVDVEEV VSPNVQREQQ ARKDETTEKL QAAQEALDSC IRFSSMALTG LSEILSYGHP
VRGVAAVELG KLLVVDEPWP TPSAASTSSS PSPSPPPAIS PAPSSSFPPS GPPRLKLAHS
TLVNALNELK IGFGTDINGE SIGELGKEVR KMLVDVEKEL SVWEDGVKRA LEDARLAQKG
AQQK
//
