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Database: UniProt
Entry: A8PC75_COPC7
LinkDB: A8PC75_COPC7
Original site: A8PC75_COPC7 
ID   A8PC75_COPC7            Unreviewed;       513 AA.
AC   A8PC75;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=Cytosine permease {ECO:0000313|EMBL:EAU81388.1};
GN   ORFNames=CC1G_05218 {ECO:0000313|EMBL:EAU81388.1};
OS   Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC
OS   9003) (Inky cap fungus) (Hormographiella aspergillata).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Agaricomycetidae; Agaricales; Psathyrellaceae;
OC   Coprinopsis.
OX   NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU81388.1, ECO:0000313|Proteomes:UP000001861};
RN   [1] {ECO:0000313|EMBL:EAU81388.1, ECO:0000313|Proteomes:UP000001861}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC   {ECO:0000313|Proteomes:UP000001861};
RX   PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA   Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W.,
RA   Borodovsky M., Burns C., Canback B., Casselton L.A., Cheng C.K.,
RA   Deng J., Dietrich F.S., Fargo D.C., Farman M.L., Gathman A.C.,
RA   Goldberg J., Guigo R., Hoegger P.J., Hooker J.B., Huggins A.,
RA   James T.Y., Kamada T., Kilaru S., Kodira C., Kues U., Kupfer D.,
RA   Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J., Mackey A.J.,
RA   Manning G., Martin F., Muraguchi H., Natvig D.O., Palmerini H.,
RA   Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA   Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA   Zolan M.E., Pukkila P.J.;
RT   "Insights into evolution of multicellular fungi from the assembled
RT   chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39)
CC       family. {ECO:0000256|PIRNR:PIRNR002744}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAU81388.1}.
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DR   EMBL; AACS02000011; EAU81388.1; -; Genomic_DNA.
DR   RefSeq; XP_001840332.1; XM_001840280.1.
DR   STRING; 240176.XP_001840332.1; -.
DR   EnsemblFungi; EAU81388; EAU81388; CC1G_05218.
DR   GeneID; 6016968; -.
DR   KEGG; cci:CC1G_05218; -.
DR   EuPathDB; FungiDB:CC1G_05218; -.
DR   eggNOG; ENOG410IFN4; Eukaryota.
DR   eggNOG; COG1457; LUCA.
DR   InParanoid; A8PC75; -.
DR   OrthoDB; 488201at2759; -.
DR   Proteomes; UP000001861; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; -; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR   InterPro; IPR038271; Pur-cyt_permease_sf.
DR   PANTHER; PTHR31806; PTHR31806; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
DR   PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001861};
KW   Membrane {ECO:0000256|PIRNR:PIRNR002744, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|PIRNR:PIRNR002744}.
FT   TRANSMEM     78     97       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    103    129       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    149    175       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    187    206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    213    232       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    252    276       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    288    312       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    344    368       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    380    400       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    412    430       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    450    467       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    487    506       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   513 AA;  55360 MW;  7FF3E3B88B45ECC9 CRC64;
     MSVPLVSKPD SGCHVYDKQG DKERGDTPTI VTVREVDEST ISTRSNRQNR WTRRLLKAGV
     EGRGIVPVPP EEQTDTQFYK LFFLFFTWNI NILTFSAGTL GPVIFGLGLG DSCLAIIFFN
     ALFCIPGSYE VTWGPKLGMR TMVLARYSFG YYGTMPLAFL NLVTMIGFSI MAAIVGGQAL
     ASITDGLSWA IGIVVVCIVS LLVSFCGVKV LNWLSLIGWI PFLTTFIIAA GFGGKHFPNP
     PPATTPLTAS AIIGYASSLA GFTITYCPLA TDASVYYRPN VSAWRVFLYV YSGLVLSLIP
     IQCLGAATAI AATTIPEWQQ RYGGADVGAL LGAVLQPLGG FGKFLSVLLA LSITPNIAAT
     SYSITVIWQA CIPRFAAIPR YVYAVVSTAI MIAIAIPGAS KFYDTLTNLL GLTGYWAAAF
     IAVIFLEHIY FRRQDSRNYE VAAWNDPRKL PLGIAAAAAS IGSFAVVVPC MDQTWFTGPI
     AKITGDIGFE VAMAATGLLY VPLRLIEKRV TGR
//
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