ID A8PCQ9_COPC7 Unreviewed; 1050 AA.
AC A8PCQ9;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 2.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Ariadne-2 {ECO:0000313|EMBL:EAU81351.2};
GN ORFNames=CC1G_11608 {ECO:0000313|EMBL:EAU81351.2};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU81351.2, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU81351.2, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- SUBUNIT: Associated with the spliceosome.
CC {ECO:0000256|ARBA:ARBA00011524}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU81351.2}.
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DR EMBL; AACS02000011; EAU81351.2; -; Genomic_DNA.
DR RefSeq; XP_001840451.2; XM_001840399.2.
DR AlphaFoldDB; A8PCQ9; -.
DR GeneID; 6017095; -.
DR KEGG; cci:CC1G_11608; -.
DR VEuPathDB; FungiDB:CC1G_11608; -.
DR eggNOG; KOG1812; Eukaryota.
DR HOGENOM; CLU_004235_2_0_1; -.
DR InParanoid; A8PCQ9; -.
DR OMA; DCPKCTT; -.
DR OrthoDB; 1789161at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.1370.210; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00356; ZnF_C3H1; 3.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 3.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 142..169
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 362..389
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 413..440
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 491..567
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 953..994
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT ZN_FING 142..169
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 362..389
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 413..440
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..238
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1050 AA; 116235 MW; 2146DEB3E7FD57E6 CRC64;
MVVGDPRTAL GVKQATNGNT GQNRISHVKK RSNGSTGHSI VPKVQSKENA QAGPPISEKG
VAVVSEAHTP HITSGPSSSF KDNRVSACET SSSPAGESNE EETSSISTTN MDKPLLVVHE
PNGPAPYRPF TAFGVTAFRT RARLNEICIL YLVKACPRGQ NCNRIHPTNV RYYKELLQDK
AATPIFYNET PGPEADEGES SSDEESQTDG ADATEDHGTE PPSSPPPPSS PPITPDNSPL
EEKPSTIQPR GSREPEQWDV ALSADAWVDS DSGSSAVEEC QAEIDPPRPV SPGSSHTEEE
VETTSITTSR RLGPGRDFSS DEGPRKPRAP FSERSINYEP SLAPSSTAQN QASSQVGPVQ
RPGQHGVCHK WLEGKCWRGR SCPYSHPQLP LPSGTESFDA ALRPAPTRGP PPPPNSSVCV
KWLQNLCDRG ADCTYVHEDV DYDYTLPRRP LLPVPIKKQP ETMMRLIHKH IRVKISDGFE
VVSITTGFET SWVYIGNVPR KVTPEAMARL LRRHGEFTDI RLPEQITTAL ITVRVRFSSP
LEASKACTTL NGLEVFGSTI SARLSLDTVG HDKTPTLLND TSVRISWEAA SKMAYGGFSS
RQQADQAIDK CRRVPFADRL LRATIHTGLP AVGRFTVRFE GVPADTKPQE MKQFLSADDV
MWGQVNYTSP DNGISGIQRL LKYNHSDILQ FDVLPPPYKG GIITAWAQLP TSAEATALCE
RLHGRKPTCI GRTRINARHM QTLEYSLNNE MYSRVQRELE ELKTSAARKH LVVSIRPRPT
CVTVRLSGED VKELGQLKAE LDIVLSGEVV RDNGKIAWDP FFFHGEGIRF VQALQRAHPL
ARVSIDKIRR QIRISGCAAD RQSLRTKLLS KLKELQSQLV YTLALDGHVI GLFLHHELPG
LRRSLGEENV FLDLWNRQLR IRGNTAAKDE ACDARTRARR RLGMDRRRPL VECPVCFDAV
SVPITLSCGH SWCKTCMVRY MLTAIDQKFF PITCLGNDAK CEEKIPLSCA SQLLCKADFE
TLIETAFSAR RKGAVRRVDE EQRRETMSWV
//
