ID A8PGF4_COPC7 Unreviewed; 1133 AA.
AC A8PGF4;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Vacuolar membrane protein {ECO:0000313|EMBL:EAU80634.2};
GN ORFNames=CC1G_10201 {ECO:0000313|EMBL:EAU80634.2};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EAU80634.2, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EAU80634.2, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- SIMILARITY: Belongs to the VPS11 family.
CC {ECO:0000256|ARBA:ARBA00007070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU80634.2}.
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DR EMBL; AACS02000002; EAU80634.2; -; Genomic_DNA.
DR RefSeq; XP_001841204.2; XM_001841152.2.
DR AlphaFoldDB; A8PGF4; -.
DR STRING; 240176.A8PGF4; -.
DR GeneID; 6017881; -.
DR KEGG; cci:CC1G_10201; -.
DR VEuPathDB; FungiDB:CC1G_10201; -.
DR eggNOG; KOG2114; Eukaryota.
DR HOGENOM; CLU_001287_0_0_1; -.
DR InParanoid; A8PGF4; -.
DR OMA; ENECPAC; -.
DR OrthoDB; 5491867at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0099023; C:vesicle tethering complex; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd16688; RING-H2_Vps11; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR016528; VPS11.
DR InterPro; IPR024763; VPS11_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR Pfam; PF00637; Clathrin; 1.
DR Pfam; PF12451; VPS11_C; 1.
DR Pfam; PF17122; zf-C3H2C3; 1.
DR PIRSF; PIRSF007860; VPS11; 3.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50236; CHCR; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001861};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 1038..1073
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 644..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..736
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1133 AA; 124201 MW; 6072B991CB9C0321 CRC64;
MSTTNATTSN VAPAWRQFSF FDVVPVKDPH DLDSSPYIFK VATEISTIAP SSAGMLVADI
HGSVHLLNRD FETLSSWVAH TGGRVTHMVE QNGILVTLGE EDTVKSPLLK IWDLDNRDKK
NGAPILLRSA KVQQSNRPHP VTTVASSSGL THLAIGLGDG TVILYRHLDQ SLSSSSSLTA
LPKARTIHES PTEPITGLGF KEPTDDTPST HLFIVTTNRV LTYQVSGRGS GGSPVTVDEI
GCGLGCATMD WRARDIVVAR DEAIYLCGTD GRGACYAYEG VKSSVHTHLS YLVIVSPPFF
PSASAASATV RNYVARSGSN ANETDITKVT VFDLENKLVA YSGTFRQGVR EVVSQWGKVY
VLSTDGKLLS LEEKSTASKL EMLYHKSLYV VALNLAKTQN LDETSVADIH KQFGDHLYAK
GDYDNAMQQY IQTIGVVQPS YVIRKFLDSQ RIHNLVTYLQ ELHTLGLANS DHTTLLLNTY
TKLKDVARLD SFIKAESRRS DTGHGEEELP FDLDTAIRVC RQAGYFEHAS YLARKYERHE
DYLRIQVEDA GNVKDALEYL RKLGPEAAES NLARYGRAML EALPEETTQL LIDLCTKSPS
SLDPDAAANA PLAIKQPTPT TATTTTSYLS YLALNRSTTV PTVVSSSETQ TVAAPPSPSI
KTLRAEGASG RRDGSVDGAT PPPSGSAFGV STAVVGANVD VGTALAHGAG AGAVSGLPPR
SSTAPPEPPA GPPPVQRLSP SLYFSHFVDH MQQFVVFLET VAVRRWGQSV DDRDNSGEVG
VWSEKGQGQG PQENENQGAE DTHHLDDIAQ AQDRQDQIAV WNTLLELYLT LPAKDNESDR
AVFDESKMRE KALRVLRSRE IPYDTTHALI LCSTHAFTDG LVLLWEKLGM VEDVLRFWID
RHNSDPLSYP NASNKVVENL MLYGPQHPNL YPLVLRFLTS TEELLRKHEE DVRGVLEVVG
EEGVMPPLAV VQVLGRNGVA SVGLVREWLV SRIRGMRGEV QNDQELTHSY RLETESKLKL
VKELSDPDQP RVFHVTRCSV CHAQLDLPSI HFMCGHSYHQ RCLGDNETEC PTCIQEQSVI
REIRRNNERL ADLHDVFLSE VRESGFEAVA EAFSRGMFGR GGSEGEGVPV VVG
//
