ID A8PL22_9COXI Unreviewed; 809 AA.
AC A8PL22;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=CagE, TrbE, VirB component of type IV transporter system {ECO:0000313|EMBL:EDP46494.1};
GN ORFNames=RICGR_0330 {ECO:0000313|EMBL:EDP46494.1};
OS Rickettsiella grylli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Rickettsiella.
OX NCBI_TaxID=59196 {ECO:0000313|EMBL:EDP46494.1, ECO:0000313|Proteomes:UP000054075};
RN [1] {ECO:0000313|EMBL:EDP46494.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Seshadri R., Federici B.A.;
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDP46494.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Myers G.S.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC {ECO:0000256|ARBA:ARBA00006512}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP46494.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQJ02000001; EDP46494.1; -; Genomic_DNA.
DR RefSeq; WP_006035470.1; NZ_AAQJ02000001.1.
DR AlphaFoldDB; A8PL22; -.
DR STRING; 59196.RICGR_0330; -.
DR eggNOG; COG3451; Bacteria.
DR Proteomes; UP000054075; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd00267; ABC_ATPase; 1.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR InterPro; IPR002789; HerA_central.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR043964; P-loop_TraG.
DR PANTHER; PTHR30121:SF6; TYPE IV SECRETION SYSTEM PROTEIN CAGE; 1.
DR PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR Pfam; PF03135; CagE_TrbE_VirB; 1.
DR Pfam; PF01935; DUF87; 1.
DR Pfam; PF19044; P-loop_TraG; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 300..384
FT /note="CagE TrbE VirB component of type IV transporter
FT system central"
FT /evidence="ECO:0000259|Pfam:PF03135"
FT DOMAIN 449..484
FT /note="Helicase HerA central"
FT /evidence="ECO:0000259|Pfam:PF01935"
FT DOMAIN 564..746
FT /note="TraG P-loop"
FT /evidence="ECO:0000259|Pfam:PF19044"
SQ SEQUENCE 809 AA; 92101 MW; 631F8C9FDD851D17 CRC64;
MWNKKRHPHS MGFSDLLNYA HFVDDGVIIN KDGAFLMAYR FRGPDLYSAS RGQLDALTVV
VNRMAGILED GWMLHVDEVR IPSLNYSAAA VFPSKVAELI DEERRRTYEK LGNHYENLQF
LSFVWKFPLS VVKKTRHWFI EGLGNEKDHD LTYLLHCFLK NVDRCVGLLR AQFSLEKLSS
IDLLSYLKLC ITGEIAPASM PPEGCFLDVV LASRSVVAGY HPRVGENTIF LLSIIGYLNE
ETIPGLLEEL GTYPLVYRWS NRFIPFSEAT AEREIKRYVR NWNNKIRGFS GVLKEALWGK
VSNKVDHDAM QMSQQAMAAS ALNRSARTRF GYWSSALVLM HPDIPLLIQA ARDLTAYLEQ
SGFSCVQEDI HAFDAWLGTL PGHGSCHLRR VFINSMNLAH VLPLQTVWTG ATYSSTESLL
PACSPPVFYA ETSGKTPFRF HMDVEDVGHQ VILGPTGSGK STYLGFLIAQ FLRYHGAQIF
VFDKDYSQRG LTAALEGYHY DIGQSETLAF CPLEDLSSEA KQLRAIQFIE DLVFLQNVNL
TPEIRHAIGS VVASLAENNH KHSRTLTVFR SEIQNEVVRS ALNYYTLEGQ FKLLDASSNA
IQTDAYLQTF EMSWVLKQKP EIAIPLLRTI FDRITTSLED NHRQGPRLII LEEAWLYVSH
PLFVRQLKDW LKTCRKKNAR VVFATQSLAD LYDPSNKGLT ETTATILESC PTKIFLPHPS
MDAEIKTLYQ KIGLTERQLE IIMHSIPKQH YYLTSPEGHR LIDLNLERLT LAFVGLSREK
TNALLRCRAT YASDWLSHWL QQEELIAYR
//
