ID A8PWM0_MALGO Unreviewed; 469 AA.
AC A8PWM0;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=MGL_1147 {ECO:0000313|EMBL:EDP44665.1};
OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP44665.1, ECO:0000313|Proteomes:UP000008837};
RN [1] {ECO:0000313|EMBL:EDP44665.1, ECO:0000313|Proteomes:UP000008837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT virulence traits shared with plant and human fungal pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family.
CC {ECO:0000256|ARBA:ARBA00005800}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP44665.1}.
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DR EMBL; AAYY01000003; EDP44665.1; -; Genomic_DNA.
DR RefSeq; XP_001731879.1; XM_001731827.1.
DR AlphaFoldDB; A8PWM0; -.
DR STRING; 425265.A8PWM0; -.
DR GeneID; 5856184; -.
DR KEGG; mgl:MGL_1147; -.
DR VEuPathDB; FungiDB:MGL_1147; -.
DR InParanoid; A8PWM0; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000008837; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000008837}.
FT DOMAIN 393..452
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 395..453
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 52630 MW; 4F581C3B2E4430B9 CRC64;
MGGEQESQEG APRLDVERLS ASSSQGLPHE ETGKVQFHTG ANCAPAPSSS SPSNQCRLPP
IDTPRPLPPH YKYPSRAPLS RLPLFKSNSL PVFTNNYNTS FGRDIGSTEA DAGSAQSGLL
RGNAGRYQMR NLLDSPSSFT REHETRFAPD PHRVFSPVYQ DMVSRRMHPY ASTERKNWDN
PRCLSRTSAF NDSNMDESIE CLKRRLSYQP SLYTHAWNRS FRPTDQFSAD FQFRRPNLRY
SRMPGRQYMS WTENSHRGYP GSFKDSIGTP FDEWHQHPFY HNGPTLLQTP QERLSANSSV
SKTLSDETST HGPKSPSATM PATFSTASRP PDNDAHGHSV STSSDRSPVH DTEGLKYPSV
IKPAPPGFSH DQHTSQFFTP KNQYQMANSS EQPVPPKRGG KLPKHITDML KTWLLDHADH
PYPTEEEKRA FCDFTGLDIC QISNWFVNAR RRILVPQSSR AAPAAPAPS
//
