ID   A8PX80_MALGO            Unreviewed;       533 AA.
AC   A8PX80;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MGL_1356 {ECO:0000313|EMBL:EDP43959.1};
OS   Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP43959.1, ECO:0000313|Proteomes:UP000008837};
RN   [1] {ECO:0000313|EMBL:EDP43959.1, ECO:0000313|Proteomes:UP000008837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX   PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA   Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA   Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA   Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA   Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT   "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT   virulence traits shared with plant and human fungal pathogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDP43959.1}.
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DR   EMBL; AAYY01000004; EDP43959.1; -; Genomic_DNA.
DR   RefSeq; XP_001731173.1; XM_001731121.1.
DR   AlphaFoldDB; A8PX80; -.
DR   STRING; 425265.A8PX80; -.
DR   GeneID; 5855480; -.
DR   KEGG; mgl:MGL_1356; -.
DR   VEuPathDB; FungiDB:MGL_1356; -.
DR   InParanoid; A8PX80; -.
DR   OMA; QRECVIS; -.
DR   OrthoDB; 3904425at2759; -.
DR   Proteomes; UP000008837; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR   PANTHER; PTHR23327:SF50; TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3; 1.
DR   Pfam; PF03105; SPX; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51382; SPX; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008837};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          1..341
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   DOMAIN          418..457
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          68..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   533 AA;  60925 MW;  6613FF117D7D5728 CRC64;
     MQEKQPELFP DDETIDTDTI DPEESSHSGA KKQWIEAKSG RRAWGEYELF DDSFGVHPQI
     VLHVESPNAL TPVDSPDTPG SDHMSSSTSS SPGTFTRTPR KNSMASRSLR HSIQQLDLGK
     PAQEIPTIAS RDYKGAEEMN EVAPGFHHRR IVIPLKADER FFDLLILAIR RLLQLHVSQQ
     RTLTMHVESL CSTIAEVASP VNSHNDMYVW REIFSLWLEF DIFEGTREKD RGEMSVAASE
     SRLHKYLEAL EKRGLLTPHQ SIEQRGKTLA GTLDSWALQA FSPTNPLTDP RSIATLEHFL
     RLNVALVTIK RFERLNIETI RKLFKKHAKK TSLHIRENIN RISSSSKAQQ LLRAASFDSP
     IPELDWSHAS VGDVLKSLTA LAPSKFQASF QLSLPRIVSC LLTKALMPVL PSVDDYSCSV
     CTSIAWHPIR LCCGHLFCIR CLVKLQKQGM NECPLCRAPN AVRDADENNL DCDMMKYLQE
     WFPREVEEKI KENKSDRSVE QRHEKQVRRK NRWARFRTRY HPENEPQREC VIS
//