ID A8Q6M9_MALGO Unreviewed; 122 AA.
AC A8Q6M9;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=ER membrane protein complex subunit 6 {ECO:0000256|ARBA:ARBA00020827};
GN ORFNames=MGL_3012 {ECO:0000313|EMBL:EDP42812.1};
OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP42812.1, ECO:0000313|Proteomes:UP000008837};
RN [1] {ECO:0000313|EMBL:EDP42812.1, ECO:0000313|Proteomes:UP000008837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT virulence traits shared with plant and human fungal pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EMC6 family.
CC {ECO:0000256|ARBA:ARBA00009436}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP42812.1}.
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DR EMBL; AAYY01000010; EDP42812.1; -; Genomic_DNA.
DR RefSeq; XP_001730026.1; XM_001729974.1.
DR AlphaFoldDB; A8Q6M9; -.
DR STRING; 425265.A8Q6M9; -.
DR GeneID; 5854333; -.
DR KEGG; mgl:MGL_3012; -.
DR VEuPathDB; FungiDB:MGL_3012; -.
DR InParanoid; A8Q6M9; -.
DR OMA; TAWMWIN; -.
DR OrthoDB; 2786477at2759; -.
DR Proteomes; UP000008837; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR InterPro; IPR008504; Emc6.
DR InterPro; IPR029008; EMC6-like.
DR PANTHER; PTHR20994:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6; 1.
DR PANTHER; PTHR20994; UNCHARACTERIZED; 1.
DR Pfam; PF07019; EMC6; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008837};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 122 AA; 13597 MW; B97452A6F0CE469F CRC64;
MRASFRSLAL SIAGAVAGVL GLQNLWGFGF FAISVVFVNL VLIAVNTGYR PELFFVLVPS
PVLTTSMEKL VPGKAEQLRK PLPSIKRLAY MAQWVVVQGA QENLLSFILW WTLWFGLVHV
YD
//
