ID A8Q8C4_MALGO Unreviewed; 461 AA.
AC A8Q8C4;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 22-FEB-2023, entry version 57.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=MGL_3245 {ECO:0000313|EMBL:EDP42487.1};
OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP42487.1, ECO:0000313|Proteomes:UP000008837};
RN [1] {ECO:0000313|EMBL:EDP42487.1, ECO:0000313|Proteomes:UP000008837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT virulence traits shared with plant and human fungal pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP42487.1}.
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DR EMBL; AAYY01000011; EDP42487.1; -; Genomic_DNA.
DR RefSeq; XP_001729701.1; XM_001729649.1.
DR AlphaFoldDB; A8Q8C4; -.
DR STRING; 425265.A8Q8C4; -.
DR GeneID; 5854007; -.
DR KEGG; mgl:MGL_3245; -.
DR VEuPathDB; FungiDB:MGL_3245; -.
DR InParanoid; A8Q8C4; -.
DR OrthoDB; 142354at2759; -.
DR Proteomes; UP000008837; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR PANTHER; PTHR47343:SF1; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000008837}.
FT DOMAIN 1..43
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 103..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..337
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 50880 MW; 9263357B89B527AE CRC64;
MDLGTMQKKL RSGQYKTKNQ FAHDLNLIWD NCLVYNASPT HPLRRNATFM RRKANHLLEF
LSDKHESKDL LAQWQLSSST TSNMPRVSSD VASTSADILS TSSTGTFNGS GNNNNNNNTN
NDKVGAHLEG SGMSIDPTVP LSSHPTPLPQ RYALRRTTDS SRVFHELDVN MSKLEEGTHF
SHLQPSASTS STMPTSRSTS LAPTLDVLKQ VSPSTPDPLS TALRRPPATA QQRWWSACSS
DAMLCAGTPV LRHESYEPPA RFLATESEHL TSRLPTQRPG VPRMMARNIR MLQRLYHTHN
KLYQLAEAVE LDLPIPPSLG EISSSEEEDE QEEMEVDKDV EAETKARADQ VVLEEEEHNL
HAPHNALKRP EKQRHSDTGP GPANEAIELC VPYASHAPPP RLSASYAHAQ ASWQVQTLLA
HAGFEGTHSA PVPGAGRRRY RVPNGPWSDA SSVHGPVCPP F
//
