ID A8T7R3_9VIBR Unreviewed; 556 AA.
AC A8T7R3;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AND4_19167 {ECO:0000313|EMBL:EDP58525.1};
OS Vibrio sp. AND4.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=314289 {ECO:0000313|EMBL:EDP58525.1, ECO:0000313|Proteomes:UP000005159};
RN [1] {ECO:0000313|EMBL:EDP58525.1, ECO:0000313|Proteomes:UP000005159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AND4 {ECO:0000313|EMBL:EDP58525.1,
RC ECO:0000313|Proteomes:UP000005159};
RX PubMed=20436956; DOI=10.1371/journal.pbio.1000358;
RA Gomez-Consarnau L., Akram N., Lindell K., Pedersen A., Neutze R.,
RA Milton D.L., Gonzalez J.M., Pinhassi J.;
RT "Proteorhodopsin phototrophy promotes survival of marine bacteria during
RT starvation.";
RL PLoS Biol. 8:E1000358-E1000358(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP58525.1}.
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DR EMBL; ABGR01000009; EDP58525.1; -; Genomic_DNA.
DR RefSeq; WP_009843076.1; NZ_ABGR01000009.1.
DR AlphaFoldDB; A8T7R3; -.
DR OrthoDB; 2514702at2; -.
DR Proteomes; UP000005159; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR PANTHER; PTHR34220:SF10; SENSOR HISTIDINE KINASE BTSS; 1.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..194
FT /note="Signal transduction histidine kinase 5TM receptor
FT LytS transmembrane region"
FT /evidence="ECO:0000259|Pfam:PF07694"
FT DOMAIN 229..351
FT /note="GAF"
FT /evidence="ECO:0000259|Pfam:PF01590"
FT DOMAIN 366..444
FT /note="Signal transduction histidine kinase internal
FT region"
FT /evidence="ECO:0000259|Pfam:PF06580"
SQ SEQUENCE 556 AA; 61010 MW; AFB0722953B97C3C CRC64;
MELVISLLQQ MCVYLVLAYM LSKTPIILPL LSISSRFSHK LICYVLFSGF CILGTYFGLQ
INDAIANTRA IGAVMGGLFG GPIVGFAVGF TGGIHRYTLG GFTDLACAIS TTAEGLIGGL
LHVYLIKRNK GSILFNPSVV FSITLVAEIV QMILLLAVAK PFDQAYQLVS AIAAPMIIAN
SVGAALFMSI LQDRKTIFEK YSATFSRRAL SIADRSVGIL STGFNSENAD KIARIIYEET
KVGAVAITDQ EKILAFVGIG DDHHKPNTPI SSQSTLDSMK QNNIIYLDGS EHPYQCSLAQ
DCKLGSALII PLRAGKEVVG TIKLYEPKRK LFSTANMSMA EGIAQLLSSQ ILYGDYQQQQ
TLLAQAEIKL LHAQVNPHFL FNALNTISAI TRRDPDKARE LIQDLSQFFR SNLKQNINTV
TLKEELAHVN SYLSIEKARF TDRLEIKIDI APELLDIKLP SFTLQPLVEN AIKHGISNML
AGGKVSIYSQ THPQGALITV EDNAGSYEPP KENHSGLGIE IVDKRLSNQF GRDSALKIIS
QQHQFTRMSF IIPHSR
//
