ID A8UNR2_9FLAO Unreviewed; 1334 AA.
AC A8UNR2;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Amino acid adenylation {ECO:0000313|EMBL:EDP70118.1};
GN ORFNames=FBALC1_11312 {ECO:0000313|EMBL:EDP70118.1};
OS Flavobacteriales bacterium ALC-1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales.
OX NCBI_TaxID=391603 {ECO:0000313|EMBL:EDP70118.1, ECO:0000313|Proteomes:UP000003630};
RN [1] {ECO:0000313|EMBL:EDP70118.1, ECO:0000313|Proteomes:UP000003630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALC-1 {ECO:0000313|EMBL:EDP70118.1,
RC ECO:0000313|Proteomes:UP000003630};
RA Azam F., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP70118.1}.
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DR EMBL; ABHI01000004; EDP70118.1; -; Genomic_DNA.
DR STRING; 391603.FBALC1_11312; -.
DR eggNOG; COG1020; Bacteria.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000003630; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000003630}.
FT DOMAIN 979..1054
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT COILED 492..519
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1334 AA; 150623 MW; 925135E840D63E34 CRC64;
MKPPTITKNN IYFNPFIGGP TIEKVIYTTQ SQVEIWIDCK IGGEDANRAY NESISLILEG
ELSISALENA VQKLVKRHEA LRAVFSPDGR FMSVLHYVPV EIEHLNFSQS SSSNIKSTLS
NYLLDDVNYI FDLVKGPLFK VGLIKINDLE HQLIITAHHI ICDGWSVGVI LEELGALYSA
SVTNVNPSLP KVDDFSSYAD ELHAYIGSEA HLKTEKFWLD QYKTSVPKLT LPTDFSRPKL
RTYKSNRLDF SINKEVISRL KKVGVKSGCS FVTTLMAAFE VFLFKQSGQD DIVLGLPSAG
QSVTGKTQLI GHCVNLLPLR SKLDASQSFS EYLKHRKLSI LDAYDHQQLS FGELLQILPL
RRDPSRVPLV PVVFNIDIGM TSQVKFTNLK YKLITNPRTF EAFELFLNAS GTEEDFILEW
SYNSTLFTSS TIKQMMVTFE EILDLIIENS THTIAEIIKI DEAAYNQLND TEAIYPNLPL
HELLSKQAKV FYKKQAIKFD ETEISYEKLE QQVNQLAHRL SSIGVSAGDF VGVCLSRSIE
LVITLRAIMQ CGAAYIPLDP SYPLQRLNYM LDDSESKFLI STSIVSSKLS TNATVLILDD
LFLNLSDFPK KPISIKVDPE DIAYLIYTSG STGKPKGVAV THKNLVNFLY SMMEKPGIKE
TDRLLSITTI SFDIVGLELF LPLLSGATLV LANDETVKDG RIMLDLIKDE GVTILQATPT
TWQMLLDIGW NIALPIKALS GGEPLSLSLS KRLLANVSEL WNMYGPTETT IWSSTKQILR
DEDVITIGNP IANTQVYILN EQNILMEPGK TGEIVIGGDG VSEGYWKRLD LTNEKFFNNP
FAIDSNTKLF RTGDLGQLLP SGELLCLGRI DHQVKVRGHR IELEEIERII DVLDDVNHSL
VIVKADNLIA YIISEKIDEL SKDQVNQWKK AIAEQLPTYM IPQEFHLISE FPMTLNGKVD
RNALLNKSTT QVHIANYTSP RNETEHIISE IWCEALNMEK IDVYSNFFEL GGHSIIAIKV
ISQIENKMGE ILPLSALMVY PTIEKLASSI DRSVKKQSLG SLVPLKPEGT KTPLYIVHGA
HFDVYLFNDL ARELDEDQPV YAIQPKGLNG IDEPLDSIYE MAAYYIAKME ISNPDGPYAL
AGFSMGGIIA YEMAKQLKAK GKKVTMLASF DSYVYPSYFY NNTTKKKIVS FFYSISQMIF
ISLNMFSSKK NFKRRIKLSK QYIYGLYLRL KVGRERQFKL QHNRTLKMNK KHIIATYQYT
MMPEDIVVDL FKAKENVFFA HDFKFLGWKK FALKGVRKHM VPGNHVDMFV SPNVEVYASN
LQRVLDNSNL ESFE
//
