ID   A8UPU1_9FLAO            Unreviewed;       823 AA.
AC   A8UPU1;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   13-SEP-2023, entry version 55.
DE   SubName: Full=Tyrosine-protein kinase {ECO:0000313|EMBL:EDP69657.1};
GN   ORFNames=FBALC1_05713 {ECO:0000313|EMBL:EDP69657.1};
OS   Flavobacteriales bacterium ALC-1.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales.
OX   NCBI_TaxID=391603 {ECO:0000313|EMBL:EDP69657.1, ECO:0000313|Proteomes:UP000003630};
RN   [1] {ECO:0000313|EMBL:EDP69657.1, ECO:0000313|Proteomes:UP000003630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ALC-1 {ECO:0000313|EMBL:EDP69657.1,
RC   ECO:0000313|Proteomes:UP000003630};
RA   Azam F., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDP69657.1}.
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DR   EMBL; ABHI01000006; EDP69657.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8UPU1; -.
DR   STRING; 391603.FBALC1_05713; -.
DR   eggNOG; COG0489; Bacteria.
DR   eggNOG; COG3206; Bacteria.
DR   OrthoDB; 9794577at2; -.
DR   Proteomes; UP000003630; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05387; BY-kinase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR025669; AAA_dom.
DR   InterPro; IPR032807; GNVR.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005702; Wzc-like_C.
DR   NCBIfam; TIGR01007; eps_fam; 1.
DR   PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR   PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR   Pfam; PF13614; AAA_31; 1.
DR   Pfam; PF13807; GNVR; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EDP69657.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003630};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT   TRANSMEM        31..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..542
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          460..538
FT                   /note="Tyrosine kinase G-rich"
FT                   /evidence="ECO:0000259|Pfam:PF13807"
FT   DOMAIN          608..761
FT                   /note="AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13614"
SQ   SEQUENCE   823 AA;  93462 MW;  13FA0AF2A49AAC00 CRC64;
     MNNRGYDDID EIDSQRVSFD FKGYLFKALN LWKFVLLCIG AALLVAYFVN VRKENIYRLN
     SLITIDNDQS PFFTANTSIS FNWGGVSEKV GSILTEIKTR THNELVVDSL EFYKQYLKQG
     KYHLIDVYNG APFEIETDKS KPQLLGKAIG IKLINNKSFE LFYEFETQKG LGQIYDSKKK
     ISVHLNPGLF SKVYKFGEPI KTSFFNGVVN IKSDALIIKN DTYFIKYLNF DSVVNQYKNN
     IQIIPNSNES TSVLKLSLIG KNKSKIVDFL NATSAILSRT ELERKNLYAT NTIKFIDSSL
     GAVNNDLKAV TDEMNDFRKV NKVFNVEEEM IQKSEQLKNY DQEKLIEESK LNYLNSLESY
     LITKTDYSNI AAPTSVGIEE INILSSVSKI IALSVERRNL EYSTKEGSIL FNDIDRQIDT
     EKNVLLETIR GTKKTIGVQL NSINRKISSL ESELIGLPKD QQEYLRIQRK LDLSREAYEV
     YQVKRGEAAI VKAANVSDIT VIDEAKDIGD PPIGPNKSLN YMMGLMIGFF SPMFLIFVLY
     LLDNTIHGSE EVERMSNIPI LGLIGRLNHK NNLVAYEKPK SAVAESFRAI RSSLQFIFKN
     KTNDSGARTI MITSSVSGEG KTFTSINIAT VYALSGKRTI LLGLDLRKPK IFGDFNIRNE
     KGVVNYLIEE STLDEITIHT HIENLDLITS GPIPPNPSEL LMGEKLKKMI SILKQEYDII
     ILDTPPLGLV ADALELAEYA DATIFMVRLD YTKKGMLQLV NAKYRSGELK NISFVLNFYK
     HKRDHNYGYG YGYGYGYGVY GNAYHEKEQV SLLDRIKIFL KRK
//