ID A8WMS6_CAEBR Unreviewed; 499 AA.
AC A8WMS6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Elongation factor Tu, mitochondrial {ECO:0000256|ARBA:ARBA00017898};
GN Name=tufm-1 {ECO:0000313|WormBase:CBG00491};
GN Synonyms=Cbr-tufm-1 {ECO:0000313|EMBL:CAP21781.2};
GN ORFNames=CBG00491 {ECO:0000313|WormBase:CBG00491}, CBG_00491
GN {ECO:0000313|EMBL:CAP21781.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP21781.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP21781.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP21781.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; HE600978; CAP21781.2; -; Genomic_DNA.
DR AlphaFoldDB; A8WMS6; -.
DR STRING; 6238.A8WMS6; -.
DR WormBase; CBG00491; CBP00101; WBGene00023870; Cbr-tufm-1.
DR eggNOG; KOG0460; Eukaryota.
DR HOGENOM; CLU_007265_0_0_1; -.
DR InParanoid; A8WMS6; -.
DR OMA; FHNNYRP; -.
DR OrthoDB; 167272at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IBA:GO_Central.
DR GO; GO:0070125; P:mitochondrial translational elongation; IBA:GO_Central.
DR CDD; cd01884; EF_Tu; 1.
DR CDD; cd03697; EFTU_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR041709; EF-Tu_GTP-bd.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR033720; EFTU_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 48..246
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 476..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 54851 MW; A948242A3BC0FD73 CRC64;
MQIFSLLSRN VGAFKTVTLC EQKMQQVSLL QARHLAVPGG KAVFKRDKPH LNVGTIGHVD
HGKTTLTSAI TKVLATSKGA KYRKYEDIDN APEEKARGIT INAFHLEYET AKRHYAHIDC
PGHADYIKNM ITGAAQMEGA ILVVAATDGP MPQTKEHLLL ARQVGVPLEN IVVFMNKVDE
VPDAETRELV EMDIREQLNE FGYPGDTCPV IFGSALCALE GKQPEIGEEA VKQLLDVLDN
KFVIPERKVN EEPMFAAEHV YSIVGRGTVI TGKLERGILK RGDKIEIVGG TKDGTTVKST
ISGLESFRKT VDQAEPGDQL GVLLRGLGPK DVRRGCVLLP QGHKHKVTDK VKAQLYVLKE
SEGGAKTPIA NYFSEHVFSL TWDSGASVKI VGKDFVMPGE SAELEIVELS LNSQMFIEPQ
QRFTIRKGAK TIGTGVFTDV LPPLTNEEKD PKSKKKLMKA EMERLGFNPY GELAEKRLKP
DFSNSPKDNP AAKAFEGQP
//
