ID A8WTZ8_CAEBR Unreviewed; 271 AA.
AC A8WTZ8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Protein CBR-HST-3.1 {ECO:0000313|EMBL:CAP23960.2};
GN Name=hst-3.1 {ECO:0000313|WormBase:CBG02583a};
GN Synonyms=Cbr-hst-3.1 {ECO:0000313|EMBL:CAP23960.2};
GN ORFNames=CBG02583 {ECO:0000313|WormBase:CBG02583a}, CBG_02583
GN {ECO:0000313|EMBL:CAP23960.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP23960.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP23960.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP23960.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
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DR EMBL; HE601438; CAP23960.2; -; Genomic_DNA.
DR RefSeq; XP_002630866.1; XM_002630820.1.
DR AlphaFoldDB; A8WTZ8; -.
DR STRING; 6238.A8WTZ8; -.
DR GeneID; 8572382; -.
DR WormBase; CBG02583a; CBP47233; WBGene00025609; Cbr-hst-3.1.
DR eggNOG; KOG3704; Eukaryota.
DR HOGENOM; CLU_017703_0_0_1; -.
DR InParanoid; A8WTZ8; -.
DR OMA; SLYDMHM; -.
DR OrthoDB; 10019at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF69; GH20068P; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 53..261
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT ACT_SITE 60
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 60..64
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 142
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 150
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 256..265
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
SQ SEQUENCE 271 AA; 32172 MW; C8ACECC5B6DA6E6C CRC64;
MAKFSTRCVI ACLLTIVMCV LQYDLFFWNF KFKWWFDRDQ KVPNSFDKKF PSALIIGVRK
GGTRALLDAI ALHPKVKIVR RETHFFDSNY SLGFDWYRNQ MPDIENEDEI VIEKTPAYFT
NENVPKRVYE MNPNMKLVLI VRHPVYRTVS DFTQVYYNKL EQNKSLPVLS IEAFRTNEAG
LETINMEYKP ITNSLYDVHI SKWLKYFKTD NFLFVNGDVF RANPLHELRR VEEFLGLERS
ITPNQLVFDY NKGFFCFRKT TKIRCLGQSK D
//
