ID A8X2H3_CAEBR Unreviewed; 280 AA.
AC A8X2H3;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Protein CBG06541 {ECO:0000313|EMBL:CAP26833.1};
GN ORFNames=CBG06541 {ECO:0000313|EMBL:CAP26833.1,
GN ECO:0000313|WormBase:CBG06541}, CBG_06541
GN {ECO:0000313|EMBL:CAP26833.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP26833.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP26833.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP26833.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; HE601320; CAP26833.1; -; Genomic_DNA.
DR RefSeq; XP_002647469.1; XM_002647423.1.
DR AlphaFoldDB; A8X2H3; -.
DR STRING; 6238.A8X2H3; -.
DR MEROPS; C01.A32; -.
DR GeneID; 8589468; -.
DR KEGG; cbr:CBG_06541; -.
DR CTD; 8589468; -.
DR WormBase; CBG06541; CBP49460; WBGene00028803; -.
DR eggNOG; KOG1543; Eukaryota.
DR HOGENOM; CLU_012184_3_3_1; -.
DR InParanoid; A8X2H3; -.
DR OMA; NCIHANT; -.
DR OrthoDB; 808912at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02620; Peptidase_C1A_CathepsinB; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF895; CATHEPSIN B; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 2.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 46..277
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 280 AA; 30539 MW; E72842ADEA4951E3 CRC64;
MTNGPVEASF TVYEDFYIYK KGVYQYTAGQ VVGVHAIKIM GWGTEHGTDY WLIANSWGAQ
CGSCWAFSTA EVISDRICIA TKGTQQPTIS PTDMLACCGR SCGDGCEGGY PIQAFRWWNS
RGVVTGGDFR GSGCRPYPFA PCNSYKCPEE KTPTCSLSCQ FGYSTAYAKD KRFGVSAYAV
ARNVAAIQTE IMTNGPVVGA FTMYEDMYKY KSGVYRHTAG RLLGGHAIKI IGWGTQNGIP
YWLIANSWGA DWGENGFLKM RRGVNECGIE SAVVAGMPKV
//
