ID A8X436_CAEBR Unreviewed; 242 AA.
AC A8X436;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Protein CBR-MXL-3 {ECO:0000313|EMBL:CAP27396.1};
GN Name=mxl-3 {ECO:0000313|WormBase:CBG07781};
GN Synonyms=Cbr-mxl-3 {ECO:0000313|EMBL:CAP27396.1};
GN ORFNames=CBG07781 {ECO:0000313|WormBase:CBG07781}, CBG_07781
GN {ECO:0000313|EMBL:CAP27396.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP27396.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP27396.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP27396.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the MAX family. {ECO:0000256|ARBA:ARBA00007628}.
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DR EMBL; HE601041; CAP27396.1; -; Genomic_DNA.
DR RefSeq; XP_002645994.1; XM_002645948.1.
DR AlphaFoldDB; A8X436; -.
DR STRING; 6238.A8X436; -.
DR EnsemblMetazoa; CBG07781.1; CBG07781.1; WBGene00029724.
DR GeneID; 8587993; -.
DR KEGG; cbr:CBG_07781; -.
DR CTD; 8587993; -.
DR WormBase; CBG07781; CBP01866; WBGene00029724; Cbr-mxl-3.
DR eggNOG; KOG2483; Eukaryota.
DR HOGENOM; CLU_1181134_0_0_1; -.
DR InParanoid; A8X436; -.
DR OMA; HFVILKD; -.
DR OrthoDB; 5398829at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:EnsemblMetazoa.
DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:EnsemblMetazoa.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0042304; P:regulation of fatty acid biosynthetic process; IEA:EnsemblMetazoa.
DR GO; GO:0032094; P:response to food; IEA:EnsemblMetazoa.
DR CDD; cd11406; bHLHzip_Max; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR10328:SF3; PROTEIN MAX; 1.
DR PANTHER; PTHR10328; PROTEIN MAX MYC-ASSOCIATED FACTOR X; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 49..100
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 16..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 97..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 19..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 242 AA; 27051 MW; F5810592F9653560 CRC64;
MSAAVDDMYF LSSSMKMEQQ KQYRKRHHSD SSDDDVSSPK SASPSMDDDR RAHHNELERR
RRDHIKDHFV ILKDSIPLLE GEKSSRALIL KRAVEYITVM QTRLNENQKS MDELRRRNEM
LEEKLLERET SSSSPSRIPS LGATQLPMSQ LTVPVAPIQQ LPQIAPVPQI PQTANPIALS
AIDPVQLNNL IASSQDAIVA LTQSLFGKMN TTAPSLPDSV SPPAGLYPLA YSPLDQPLAV
RF
//
