ID A8X6C5_CAEBR Unreviewed; 560 AA.
AC A8X6C5;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Protein CBG08341 {ECO:0000313|EMBL:CAP28186.2};
GN ORFNames=CBG08341 {ECO:0000313|EMBL:CAP28186.2,
GN ECO:0000313|WormBase:CBG08341}, CBG_08341
GN {ECO:0000313|EMBL:CAP28186.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP28186.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP28186.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP28186.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; HE601100; CAP28186.2; -; Genomic_DNA.
DR AlphaFoldDB; A8X6C5; -.
DR STRING; 6238.A8X6C5; -.
DR WormBase; CBG08341; CBP38322; WBGene00030153; -.
DR eggNOG; KOG1292; Eukaryota.
DR HOGENOM; CLU_017959_5_4_1; -.
DR InParanoid; A8X6C5; -.
DR OMA; TIIQCKG; -.
DR OrthoDB; 1085011at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF58; PROTEIN CBG08341; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 560 AA; 61415 MW; F555D8AF0133CD82 CRC64;
MMVSESLHFH VNDVPHFTEI ILFGLQQMLV CISALLVTPY LLSNMLCAGT ETIAIRVQLI
AATFVTTGIA TILQTTFGLR LAILHGPSFA FLPALHAFEE LYPCTSETDT NLWKEKMQLV
HSLTVIQNFS FPFQISGSLF LAVLIMPIMG VTGLVGKISK HIGPITIVPM LVLLCIGTVP
DIQEKVSLHW ISIVEILLLI VFVVLLEDLE VPIPGYSFSE KKFIYTRLQM FSQFPYLLGI
CIAWFLCFLL TITNLEPSGS PARTDLNESV FVFDQTPWIQ VQYPLQFGFP KFSFQLIIAF
TASTVVVMIE SVGNYGICAQ ISQQGSPPSS SINRAFVVEG VGSMLAALMG CGTGVTTYSE
NIAIMQVTKV TSRITMQCAG VFLILMGVVS KVAAFLAMIP EAIIGGVLAA GMSMVCGVAF
ANLQNVDLRL SRNITIVGLS IILGCTIPAH FKKNPLDTGH KTMDDVLGTL LKMRMLVGGL
IAFCLDLMAR GATRGQRGLE ERIEQRDLAI ERDGFAFSRF ANQTILKIPS ITKLPVMPSE
RSIRQVEELR SNGEKSKEKI
//
