ID A8X6G1_CAEBR Unreviewed; 533 AA.
AC A8X6G1;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Protein CBR-UGT-44 {ECO:0000313|EMBL:CAP28222.2};
GN Name=ugt-44 {ECO:0000313|WormBase:CBG08389};
GN Synonyms=Cbr-ugt-44 {ECO:0000313|EMBL:CAP28222.2};
GN ORFNames=CBG08389 {ECO:0000313|WormBase:CBG08389}, CBG_08389
GN {ECO:0000313|EMBL:CAP28222.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP28222.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP28222.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP28222.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000301};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; HE601100; CAP28222.2; -; Genomic_DNA.
DR AlphaFoldDB; A8X6G1; -.
DR STRING; 6238.A8X6G1; -.
DR WormBase; CBG08389; CBP43359; WBGene00030189; Cbr-ugt-44.
DR eggNOG; KOG1192; Eukaryota.
DR HOGENOM; CLU_012949_1_4_1; -.
DR InParanoid; A8X6G1; -.
DR OMA; SPSHYIW; -.
DR OrthoDB; 3471622at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IBA:GO_Central.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF33; GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..533
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002732695"
FT TRANSMEM 493..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 533 AA; 60068 MW; ED3E2CE907A1507C CRC64;
MSTYLYLLLL LVIPSFLLVD ANGTTKPKKV LVFLPISGHS HLKFMGTISN ILQDEGYNVT
VLLPILDEGL RDTTPLVRKI KHRILVEQND ELIEANVQFK AGGGRENTWV MNSGIVGFLK
LGTKAANICK ASCKNIFGNE TLINYLRDQH FDVAVSEPLY SCGFALFDHL GIDIAISADS
HLGLEVSKIA HGASITTSYL PAVFSSGSER MGLVGRVKNF VESYFNYHFN SKIYDYELSG
IEGLYKNGKG WRELLRKNAY MFVNSNPQMD IPSPRTSKFV DIGGISSGAF KQEKLPAEYD
RILSLRKNNV LISFGTNAKS MYMSDDMKLS LIKTFESMPD TTFIWKYENT TIDIVKQYNK
KINNVMLTDW MPQTALLSDP RLTLFVTHGG LGSTNEVAFS GKPSVMVPVF GDQTRNARML
ERHGVALLLT KYDLTDTKKG QIVLNESRKL AQMLRNQPES PKEIFIKYFN FVARFGKPHG
LDSYAAEMSF VEFYYIDFFF ILIVMSMAMY VATSRILKAT HNITNLISIK FKL
//
