ID A8XD01_CAEBR Unreviewed; 801 AA.
AC A8XD01;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Protein CBR-CYP-35C1 {ECO:0000313|EMBL:CAP30519.2};
GN Name=cyp-35c1 {ECO:0000313|WormBase:CBG11445};
GN Synonyms=Cbr-cyp-35C1 {ECO:0000313|EMBL:CAP30519.2};
GN ORFNames=CBG11445 {ECO:0000313|WormBase:CBG11445}, CBG_11445
GN {ECO:0000313|EMBL:CAP30519.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP30519.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP30519.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP30519.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE600908; CAP30519.2; -; Genomic_DNA.
DR RefSeq; XP_002635205.1; XM_002635159.1.
DR AlphaFoldDB; A8XD01; -.
DR STRING; 6238.A8XD01; -.
DR GeneID; 8577201; -.
DR WormBase; CBG11445; CBP40111; WBGene00032559; Cbr-cyp-35C1.
DR HOGENOM; CLU_351337_0_0_1; -.
DR InParanoid; A8XD01; -.
DR OrthoDB; 2900138at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IBA:GO_Central.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR GO; GO:0008395; F:steroid hydroxylase activity; IBA:GO_Central.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IBA:GO_Central.
DR GO; GO:0006805; P:xenobiotic metabolic process; IBA:GO_Central.
DR CDD; cd20617; CYP1_2-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR038717; Tc1-like_DDE_dom.
DR InterPro; IPR002492; Transposase_Tc1-like.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR PANTHER; PTHR24300:SF114; CYTOCHROME P450 FAMILY; 1.
DR Pfam; PF13358; DDE_3; 1.
DR Pfam; PF01498; HTH_Tnp_Tc3_2; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..801
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002732989"
FT DOMAIN 530..601
FT /note="Transposase Tc1-like"
FT /evidence="ECO:0000259|Pfam:PF01498"
FT DOMAIN 612..754
FT /note="Tc1-like transposase DDE"
FT /evidence="ECO:0000259|Pfam:PF13358"
SQ SEQUENCE 801 AA; 92473 MW; AC73E66B440481A1 CRC64;
MFLLLLIISI IAWLSARQYL KSKRLPPGPT SFPLIGNLHQ IGYQLWKTGG MVATLNHYRK
QYGDVFTLWL GPIPHVNITN YEISHEVFVK NATKYADKHI PPLFDFIRQG NGVFFSNGDK
WQELRRFSML TMRNMGMGRD LMEEKIIAEL NTRCSELDAK SVNGTAVETV NVFFDLTVGS
IINNMLMGFR FDERNKNRFL TFKHMVDKSM EKFSATYLVL PVWILKTLFS KSFDELISDN
FKLLDYVSED AVKRSRDYIK GTYEIDPDNV EDFVDAFLLK MKQDPKSEVY NEENLKMLVL
DLWITGQETT TMTLISAFIR FLNNPDVMDK LRNELMKVTN GASRHLSLKD KNETPYLNAT
LAEVQRHASI LNVNFWRLNK EPTVIGGHPV DSGCLIAAQL SALHTNEKVF EDPEKFEPER
FLKNENLIQQ VIPFGIGKRS CLGEALAKAE LYLVRYADMV RPFGKKSFSV DERKSIVRGH
ELGAHPKILA TQFSCSSSQI YRILKKNRDD NGVVHRQSPG RPRTTSRNMD RNILRACRED
PRRTSTDIQL SVTSPNEPVP SRRTIRRRLQ VAGLHGRRPV KKPLVSLKNR KARVEWAKQH
LSWGPREWAN HIWSDESKFN MFGTDGIQWI RRPIGSRYAP QYQCPTVKHG GGSVMVWGCF
SDTSMGPLKR IVGTMDRYVY EDILENTMRP WARANLGRSW VFQQDNDPKH TSGHVANWFR
RHRVNLLEWP SQSPDLNPIE HMWEELERRL KGVRASNANQ KFAQLEAAWK SIPMTVVQTL
LESMPRRCKA VINAKGYPTK Y
//
