ID A8XEQ3_CAEBR Unreviewed; 216 AA.
AC A8XEQ3;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=guanylate kinase {ECO:0000256|ARBA:ARBA00012961};
DE EC=2.7.4.8 {ECO:0000256|ARBA:ARBA00012961};
GN Name=guk-1 {ECO:0000313|WormBase:CBG11972};
GN Synonyms=Cbr-guk-1 {ECO:0000313|EMBL:CAP31021.1};
GN ORFNames=CBG11972 {ECO:0000313|WormBase:CBG11972}, CBG_11972
GN {ECO:0000313|EMBL:CAP31021.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP31021.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP31021.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP31021.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the guanylate kinase family.
CC {ECO:0000256|ARBA:ARBA00005790}.
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DR EMBL; HE601540; CAP31021.1; -; Genomic_DNA.
DR RefSeq; XP_002646267.1; XM_002646221.1.
DR AlphaFoldDB; A8XEQ3; -.
DR STRING; 6238.A8XEQ3; -.
DR WormBase; CBG11972; CBP39493; WBGene00032989; Cbr-guk-1.
DR eggNOG; KOG0707; Eukaryota.
DR HOGENOM; CLU_001715_0_2_1; -.
DR InParanoid; A8XEQ3; -.
DR OMA; EWAVVHG; -.
DR OrthoDB; 324675at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004385; F:guanylate kinase activity; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00071; GMPK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR017665; Guanylate_kinase.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03263; guanyl_kin; 1.
DR PANTHER; PTHR23117:SF13; GUANYLATE KINASE; 1.
DR PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..208
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 216 AA; 24941 MW; CC6304F5CA1E1CBE CRC64;
MHATSRVGWF WSTPSWQKII RRMPCRPIVL SGPSGGGKST ILTRAMKEYP NSFAFSVSHT
TRQPRAGEEH GKHYYFTEKE KMQAMIKNGE FLEHATFSGN TYGTSKKTVE EIEKSGKICV
LDIELQGVRN IKNSHLDARY ILIRAPSIKL LEERLRARGT ETEESLKKRL QHAEEDLVEI
EKNPTLFDKV IVNDDLERAY KEFVDLLRED LEKTKK
//
