ID A8XF51_CAEBR Unreviewed; 260 AA.
AC A8XF51;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Protein CBG12270 {ECO:0000313|EMBL:CAP31273.2};
GN Name=sup-18 {ECO:0000313|WormBase:CBG12270};
GN ORFNames=CBG12270 {ECO:0000313|EMBL:CAP31273.2,
GN ECO:0000313|WormBase:CBG12270}, CBG_12270
GN {ECO:0000313|EMBL:CAP31273.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP31273.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP31273.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP31273.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the nitroreductase family.
CC {ECO:0000256|ARBA:ARBA00007118}.
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DR EMBL; HE600962; CAP31273.2; -; Genomic_DNA.
DR RefSeq; XP_002642684.1; XM_002642638.1.
DR AlphaFoldDB; A8XF51; -.
DR STRING; 6238.A8XF51; -.
DR GeneID; 8584678; -.
DR WormBase; CBG12270; CBP38029; WBGene00033243; Cbr-sup-18.
DR eggNOG; KOG3936; Eukaryota.
DR HOGENOM; CLU_070764_1_0_1; -.
DR InParanoid; A8XF51; -.
DR OMA; GANHQPW; -.
DR OrthoDB; 5390904at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0140616; F:iodotyrosine deiodinase activity; IEA:UniProt.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0006570; P:tyrosine metabolic process; IBA:GO_Central.
DR CDD; cd02144; iodotyrosine_dehalogenase; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR23026:SF90; IODOTYROSINE DEIODINASE 1; 1.
DR PANTHER; PTHR23026; NADPH NITROREDUCTASE; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 68..238
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 30000 MW; 63275A0D12C06FBF CRC64;
MNKRVEKQLE SRTKQRKVEV SDKQTGDEMV FTDLHEMVIR ERMIPYRTPV INDDITLRNS
QIFYEEMKMR RSCRQFSSRD VPLKVIQNLL KTAGTSPSVG NLQPWTFCVV SSDSIKTMIR
KILEADERDN YVSRKKGASW VVDVSQLQDT WRRPYITDAP YLLIVCHEIF RDVHNKTERV
FHYNQISTSI AVGILLAAIQ NVGLSTVVTS PLNAGPDISR ILRRPENESI LLLLPLGYAS
EDVLVPDLKR KPVEHITKLY
//
