ID   A8XG04_CAEBR            Unreviewed;       808 AA.
AC   A8XG04;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 2.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Protein CBG12545 {ECO:0000313|EMBL:CAP31509.2};
GN   ORFNames=CBG12545 {ECO:0000313|EMBL:CAP31509.2,
GN   ECO:0000313|WormBase:CBG12545}, CBG_12545
GN   {ECO:0000313|EMBL:CAP31509.2};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP31509.2, ECO:0000313|Proteomes:UP000008549};
RN   [1] {ECO:0000313|EMBL:CAP31509.2, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP31509.2,
RC   ECO:0000313|Proteomes:UP000008549};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
CC       {ECO:0000256|ARBA:ARBA00007292}.
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DR   EMBL; HE600940; CAP31509.2; -; Genomic_DNA.
DR   RefSeq; XP_002640063.1; XM_002640017.1.
DR   AlphaFoldDB; A8XG04; -.
DR   STRING; 6238.A8XG04; -.
DR   EnsemblMetazoa; CBG12545.1; CBG12545.1; WBGene00033479.
DR   GeneID; 8582058; -.
DR   WormBase; CBG12545; CBP28224; WBGene00033479; -.
DR   eggNOG; KOG4160; Eukaryota.
DR   HOGENOM; CLU_018363_0_0_1; -.
DR   InParanoid; A8XG04; -.
DR   OMA; WLHRKQF; -.
DR   OrthoDB; 2880121at2759; -.
DR   Proteomes; UP000008549; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR   InterPro; IPR032942; BPI/LBP/Plunc.
DR   InterPro; IPR001124; Lipid-bd_serum_glycop_C.
DR   InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR   PANTHER; PTHR10504; BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10504:SF131; BPI2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01273; LBP_BPI_CETP; 1.
DR   Pfam; PF02886; LBP_BPI_CETP_C; 1.
DR   SMART; SM00328; BPI1; 1.
DR   SMART; SM00329; BPI2; 1.
DR   SUPFAM; SSF55394; Bactericidal permeability-increasing protein, BPI; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..808
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002733115"
FT   DOMAIN          64..293
FT                   /note="Lipid-binding serum glycoprotein N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00328"
FT   DOMAIN          495..793
FT                   /note="Lipid-binding serum glycoprotein C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00329"
SQ   SEQUENCE   808 AA;  86083 MW;  354BAA78BD32554C CRC64;
     MLKILSVCLL IGTVQSGGYA GGSNGGGGSA VQSVQGAGGS FASGPDFNPI LLQGQRGYPG
     IRARLNSRAF QYASTLVAGL LNTEIKKARI PPISQCIPMV QGCVNIYNLY VSRYRCPQRV
     VLYPAPPNRI VLQVQNVDLG VTGNLGGQVV VLLPIALSGI VQLNIHQATI TVQLAIERGP
     RGPYVRLLSC DMQIGYADAY IENGGLVGDI VNSQFRSQIS NQVRQMIPGQ VCGQLPNIIN
     EKLNSKLGAL PQTIALQQMI SLFGGALGLG GSSGGGGNCP STCPKQPVFI PSTNPQPTQV
     APAQVAPSVP IAGGSAPAPQ IPSTAYTEGQ RKAAAVRTLQ QLQALRYPRS ANITQNLVLP
     QGIGRQRMYA ATIRAAGVGQ YQSQQVATYT NVGARPRYPP PPTVAAGPVA VQPPPDCSKC
     SAAGGSSDDP ASFLRQIAGH LDMSKLNDLY LSLQYIQSYA TSNDYTVDLT GEFSPYGQGG
     TPFGPFPTQF PYYGGQMAEF IVTDYTVNSL FYWLHRKQFL SFRIGPETPK IGELLKTTCS
     DDDDDLEATS VELDEEEAKR RRRLAKEKAK YRLRRGVHTN STIVVSVRPS RHVATHNSDP
     EIIGATNETT RLRSKRMRDS RRRRQEDTAG LADLGICFGD ILPAVREKYP NKKIAVQIRT
     VRAPSVILSS AKGGMVTLDL IADADIYIDQ TNTKVGTITI AATVVLTARI GGGRLSGTAE
     ITQLHLSDRT GSLGLPQDAL DNLGNLGKEL LQKVANDGLQ KGIAISIPTN LPLPIGIINP
     DVHIVEHGLH IATDFTISPS LLGGGGGC
//