ID   A8XIN4_CAEBR            Unreviewed;      1431 AA.
AC   A8XIN4;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 2.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Protein CBR-FCD-2 {ECO:0000313|EMBL:CAP32509.2};
GN   Name=fcd-2 {ECO:0000313|WormBase:CBG13770};
GN   Synonyms=Cbr-fcd-2 {ECO:0000313|EMBL:CAP32509.2};
GN   ORFNames=CBG13770 {ECO:0000313|WormBase:CBG13770}, CBG_13770
GN   {ECO:0000313|EMBL:CAP32509.2};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP32509.2, ECO:0000313|Proteomes:UP000008549};
RN   [1] {ECO:0000313|EMBL:CAP32509.2, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP32509.2,
RC   ECO:0000313|Proteomes:UP000008549};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
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DR   EMBL; HE600943; CAP32509.2; -; Genomic_DNA.
DR   STRING; 6238.A8XIN4; -.
DR   WormBase; CBG13770; CBP44303; WBGene00034479; Cbr-fcd-2.
DR   eggNOG; KOG4712; Eukaryota.
DR   HOGENOM; CLU_252446_0_0_1; -.
DR   InParanoid; A8XIN4; -.
DR   OMA; YLYCGAY; -.
DR   OrthoDB; 2878837at2759; -.
DR   Proteomes; UP000008549; Unassembled WGS sequence.
DR   GO; GO:0000793; C:condensed chromosome; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0070182; F:DNA polymerase binding; IBA:GO_Central.
DR   GO; GO:1990918; P:double-strand break repair involved in meiotic recombination; IBA:GO_Central.
DR   GO; GO:0007129; P:homologous chromosome pairing at meiosis; IBA:GO_Central.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0031573; P:mitotic intra-S DNA damage checkpoint signaling; IBA:GO_Central.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:EnsemblMetazoa.
DR   GO; GO:0090329; P:regulation of DNA-templated DNA replication; IEA:EnsemblMetazoa.
DR   InterPro; IPR029448; FANCD2.
DR   PANTHER; PTHR32086; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   PANTHER; PTHR32086:SF0; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   Pfam; PF14631; FancD2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..431
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1431 AA;  164084 MW;  91E5FE86988BE12F CRC64;
     MSDEEFDSFD DGDDDGVLEI DEDEVENRNR PRVGRDLSMA MTQKLFGNLA GGASECHVAY
     DESAYVAPRN RFEEILAEED VRIVNDHDPE VAMETDLGAY EKFVVFGGNL NHEDLCRNLE
     KRMEADRSEI FGEFETACNR DNGLLALYMS PSKSHLGLQD TLFRAFLQIR QTQTKSFALM
     LRKLNILAKK SENSSDLMLS QTCVAHMRHL NRLFDSQAIF NTIFEFEWRF WNPVVRNSFI
     AALPEIFTEI SLQQFTAIRL NQQIQETQNV PDLASFQLQI VETLRLLRMD SLVSRQIRRD
     LCNLCMDLDV FCLPAVIAFS LGSLLAQPTG KVSGGESSDD DETLFHEMLR QLSRLLKIDA
     VKKRTNKADV ICTEIFAHFL KFLQLEKRSW KFIISWIAKK DKRKALAMKN EDSEKNEEGP
     EDVRGSSEEP QETAEEPLPE EPYLSSFEAF LIFSLLSNPE SCPPGFVTAV NSKILNIPLA
     FSPKFLKIVD LGISFKKFST THLPALIHVA RHCFWSPDAN IRQMGVAMWK QLFVGMEKKE
     RVRVFGELMK HFSQSEIECE AVLDVFFKVI KSTNSGVILE FSGQIQKCIE LIHKLSIPNI
     KRLFQVMLLM NVPNMKSAKS VLFDIDEVIN RFLISVNDRE KFLGVLALLM KIQVEMEKKH
     SENQELLVRE GIARIEDAIK TSSRLRGAFY EHLKLVLQQR KRSEEIRFFI EWSQNLLQRF
     KEDFFEFQEE MDQECTWILK PPSERLQEVI PMFELVLEME HLKTRWKEEE EENEGMGNDT
     VVTKDLDFAF EALLPSQDED LPADRDQKLD HLYFLIQMCR SVLNAFLTHS SSDDVAKIAI
     RQFKVMMEAE KKLAAGLGSG ATWRVPNLEF KEITVSGPEK PKAKGGARKR KSDETTIIGA
     TGDDLLAQEA EEEEDETEKN VPNLTLKSHF TCLRLRPLVH ILKLAQKKRG CLKYLCDELQ
     TVFDHIARSK KKAPPMLAAR AITQKIDAFY HGDAASVWFC VRKSTEHIWE IVVSMFHFFS
     TLADASQQSS VQMQKDLEEM GEKSLKLMHC LLSGDLYGGE EKLSAVEKAD RKSVIIRIIE
     KKMFGLERLS NNEEEARIEI GKFLAKSAEF SPTPAVAVAL LNVFDDLKLD EEEQAETRKV
     MAKYALAYLK KDWSKVDEQW SRGTKYTNAV KDILQHYINL RREKDQLLAI QWILTNKVVQ
     LVPEDDKRKS CVFSQQSDDE MLEKEDKKAV FYCISKTTFG VIFKTLFGCL NTRCLKYDMS
     GIAAKNRLVD EDETLESWEI ASSCFLILCL FLRINKIRTT AVLTTAIREG KQFLITVSRK
     SSFIYLMENI TKGTNFDVVC RRVEKILSAV QQGNRVLQSI GTYAKTQKCV HLLKRFPELR
     AENENCLRVI HSAMVKNECL NAFTVGLVKS RSIDGEIITN QPDSPMDSDD E
//