ID A8XKF6_CAEBR Unreviewed; 735 AA.
AC A8XKF6;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Protein CBR-KCNL-3 {ECO:0000313|EMBL:CAP33130.2};
GN Name=kcnl-3 {ECO:0000313|WormBase:CBG14678};
GN Synonyms=Cbr-kcnl-3 {ECO:0000313|EMBL:CAP33130.2};
GN ORFNames=CBG14678 {ECO:0000313|WormBase:CBG14678}, CBG_14678
GN {ECO:0000313|EMBL:CAP33130.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP33130.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP33130.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP33130.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE600983; CAP33130.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XKF6; -.
DR STRING; 6238.A8XKF6; -.
DR WormBase; CBG14678; CBP40121; WBGene00035100; Cbr-kcnl-3.
DR eggNOG; KOG3684; Eukaryota.
DR HOGENOM; CLU_398089_0_0_1; -.
DR InParanoid; A8XKF6; -.
DR OMA; YLFARFM; -.
DR OrthoDB; 2877641at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0043025; C:neuronal cell body; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005516; F:calmodulin binding; IBA:GO_Central.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR004178; CaM-bd_dom.
DR InterPro; IPR036122; CaM-bd_dom_sf.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF37; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL-LIKE PROTEIN 3; 1.
DR Pfam; PF02888; CaMBD; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF03530; SK_channel; 1.
DR SMART; SM01053; CaMBD; 1.
DR SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 499..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 563..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 602..676
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000259|SMART:SM01053"
FT REGION 709..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 83589 MW; E802DE27B9FEA3C5 CRC64;
MFAKLIGIEQ HKGHGSHSID LSTMQMEPDL SYSDVITGST DLEMERPNSR LHCHPEITYK
CTVQPYFSLH THTPTAYNNN TTRHRPSLGT LQTADTLHAR RFLSDKRRSY RNRSLGPTIA
SAPSVEQEDY RTPRPSFDSN GYAGKSFDFS SAHAGLTTSD SNPLVKVSAD FLRLNGSRQQ
FKNLLSARKK LGSLPPAYTR IDFSRESLDS HSARALSNHH GPVITVEDTG SQLRINNIKP
SVNQHLLETS CSFEKTMVTQ CERNGSVTSH NTSSAFQRNN SRYGVPIDSI AVKQVYRVRS
ERLINRVRIT DRSLYSALFG VILMLIESEL TAERVYGVSK DHWISQSLRV GVAFSTIILL
FHIVLYHLND ITLELVDCGA DDWRVVVTTE RVIQFCAEFV CCAICPLPGS GEMKWTFIEP
SLHKDGTSEG RTISTRSVEV PVDIILSCLM LCRSYLFARF MVLHSKQFQD ASTRTLAALN
RIQVNFSFVI KTSLDQQPVL FLTSFTFIFW IIMSWMFVQC ERYGFSEKNP QSILYSNSLW
FIAITFMLNG YGDIVPQTNA GRFIAIFVGV VGAVISSILI AVISRNILLS QGQRNVNNFM
YDSKLSREHK EAAARVLQHT WHIHKCLQGG EGGNRRLRTY QRKFLKAIHR FRAVKSEMRE
FSENNAQNNP QMTRLVTDMH TSMQRLLNVQ EEMRMQIEVL QQSVRNHYHH STPNVPQLQG
LTSSSHPSER HDSRY
//
