ID A8XUX1_CAEBR Unreviewed; 290 AA.
AC A8XUX1;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Protein CBR-NHR-44 {ECO:0000313|EMBL:CAP36438.2};
GN Name=nhr-44 {ECO:0000313|WormBase:CBG19141};
GN Synonyms=Cbr-nhr-44 {ECO:0000313|EMBL:CAP36438.2};
GN ORFNames=CBG19141 {ECO:0000313|WormBase:CBG19141}, CBG_19141
GN {ECO:0000313|EMBL:CAP36438.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP36438.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP36438.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP36438.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993}.
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DR EMBL; HE601047; CAP36438.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XUX1; -.
DR STRING; 6238.A8XUX1; -.
DR WormBase; CBG19141; CBP40126; WBGene00038409; Cbr-nhr-44.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_7_2_1; -.
DR InParanoid; A8XUX1; -.
DR OMA; WIMHFEE; -.
DR OrthoDB; 2883131at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06960; NR_DBD_HNF4A; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR049636; HNF4-like_DBD.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45680:SF6; NR LBD DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR45680; NUCLEAR HORMONE RECEPTOR FAMILY; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 24..101
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 183..290
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 290 AA; 33798 MW; 71DD0A11234D6BFD CRC64;
MDSDSSPSTS SASSSSVSTP KLTSEKCLVC LQPAHGNHFG VDSCRACAAF FRRVFVTHKQ
QFKCREGDNK CTPDELGRWI CKKCRTDRCF ALGMKPDNIQ RDRDRMVCSE QFHEDRKRKS
HESIIPLTVE RFVGNKVMRN YSLGSGKNVE YITFFDLSSI ISDAEYILKK TPKIDKTLKL
KSSLEQLASG LREVRKTQLW KSIPEMKKIG KIETFNHWVD DMRRAGEWIM HFEEFRKLEH
GEKMEILKCM WHLFSRLERM QITAEMRRQK LCEDNEFVFG SSKASDKEIR
//
